CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5285
Family Name Gonadotropin-releasing hormone receptor ligand AGN-PC-075RJQ family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00362875 Functional Category Bioactive
Superfamily NF-kappa-B and Retinal dehydrogenase 1 Binder Superfamily
Class Class 44

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Phospholipase A2 Inhibitor Quinacrine Family 13 95
DNA Binder Elliptinium Acetate Family 11 116
Indeglitazar family 3 39
Nicotinic acetylcholine receptor alpha2 / alpha3 Ligand Ibogai... 3 21
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 11 41
Oestrogen receptor and Estrogen receptor beta Ligand Pipendoxi... 11 48
Oestrogen receptor and Estrogen receptor beta Ligand 4-(3-phen... 5 14
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
5-hydroxytryptamine receptor 2A and Alpha-2A adrenergic recept... 4 29
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Kinesin-like protein KIF11 inhibitor AGN-PC-080PZM family 1 11
Vascular endothelial growth factor receptor 2 ligand indolyl q... 2 1
Hypoxia-inducible factor 1-alpha and Lethal factor inhibitor C... 1 1
Substance-P receptor ligand 1-[4-(2-methoxyphenyl)piperazin-1-... 11 12
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 5
Transient receptor potential cation channel subfamily V member... 1 5
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
D(2) dopamine receptor and D(4) dopamine receptor ligand AGN-P... 1 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
Acetylcholinesterase and Cholinesterase inhibitor P10358 family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00362876 CHEMBL147537 Bioactive AGN-PC-075RF7
CFAMM00362875 CHEMBL149447 Bioactive AGN-PC-075RJQ
CFAMM00362874 CHEMBL280296 Bioactive [2-(3,5-dimethylphenyl)-3-[2-[4-(4-hydroxyphenyl)butylamino]ethyl]-1H-indol-5-yl] 4-ethylsulfonylpiperazine-1-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48712 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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