CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5290
Family Name Collagenase 3 and Stromelysin-1 inhibitor (2R,4S)-N-hydroxy-4-[[(2S)-2-hydroxypropanoyl]amino]-1-(4-propoxyphenyl)sulfonylpyrrolidine-2-carboxamide family
No. of Seeds 7 No. of Other Members 0
Family Centroid CFAMM00254924 Functional Category Bioactive
Superfamily Disintegrin and metalloproteinase domain-containing protein 17 and Matrix metalloproteinase-14 Inhibitor N-hydroxy-2-(4-methoxyphenylsulfonamido)acetamide Superfamily
Class Class 2682

Cousin Family NamesSeedsMembers
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
Disintegrin and metalloproteinase domain-containing protein 17... 25 33
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 16
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 13
Disintegrin and metalloproteinase domain-containing protein 17... 10 39
Collagenase 3 and Interstitial collagenase inhibitor N-hydroxy... 8 4
Pol polyprotein inhibitor morpholinone scaffold 1 family 5 29
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 4-acety... 9 4
Collagenase 3 and Matrix metalloproteinase-9 inhibitor (4R)-N-... 13 4
Pol polyprotein inhibitor benzyl (2S)-2-[[[(2S)-3-[cyclopentyl... 2 6
Matrix metalloproteinase-9 and Collagenase 3 inhibitor N-hydro... 2 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor (5R)-N-... 7 0
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-1-... 25 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 7 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 14 0
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R,4S)... 3 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4Z)... 17 0
Disintegrin and metalloproteinase domain-containing protein 17... 4 2
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
Collagenase 3 and Disintegrin and metalloproteinase domain-con... 4 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 0
Collagenase 3 and Neutrophil collagenase inhibitor (3R)-1-hydr... 1 0
Macrophage metalloelastase and Collagenase 3 inhibitor (2S)-N-... 2 2
Disintegrin and metalloproteinase domain-containing protein 17... 13 1
Neutrophil elastase inhibitor 1-[(2S)-2-[(4-methoxyphenyl)sulf... 2 11
Neutrophil collagenase and Interstitial collagenase inhibitor ... 3 0
72 kDa type IV collagenase and Collagenase 3 inhibitor 2-[[2-(... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00362887 CHEMBL356520 Bioactive (2R,4S)-1-(4-butoxyphenyl)sulfonyl-N-hydroxy-4-[[(2S)-2-hydroxypropanoyl]amino]pyrrolidine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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