CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5342
Family Name Sigma non-opioid intracellular receptor 1 ligand SureCN5315520 family
No. of Seeds 3 No. of Other Members 11
Family Centroid CFAMM00363215 Functional Category Bioactive with Natural Product
Superfamily Muscarinic acetylcholine receptor Ligand Flutropium Bromide Superfamily
Class Class 237

Cousin Family NamesSeedsMembers
Opioid receptor ligand synthetic opioid methadone analog Dextr... 2 108
Alpha-2 adrenergic receptor ligand opiate Meperidine Family 13 76
Muscarinic acetylcholine receptor Ligand Flutropium Bromide Fa... 6 45
Sodium channel protein type 5 subunit alpha Ligand Hexylcaine ... 4 94
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Muscarinic acetylcholine receptor Ligand Mepenzolate Family 35 11
Muscarinic acetylcholine receptor M1 Ligand Oxyphenonium Family 12 5
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Sulfen... 5 13
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Sodium-dependent noradrenaline transporter Inhibitor (r)-1-((s... 3 8
Cholinesterase Inhibitor 4-[4-(benzyloxy)piperidino]butyl-3-fl... 5 18
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Sigma non-opioid intracellular receptor 1 ligand (1R)-1'-benzy... 7 27
Sigma non-opioid intracellular receptor 1 ligand 2-[(3R)-1'-(c... 2 0
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-076TWX... 8 5
Sigma non-opioid intracellular receptor 1 ligand methyl (1R,2S... 4 0
Renin and Potassium voltage-gated channel subfamily H member 2... 6 0
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-0793IB... 2 0
Melanin-concentrating hormone receptor 1 ligand 2-(3,4-difluor... 4 0
Urotensin-2 inhibitor 3-(4-bromophenyl)-3-[2-(dimethylamino)et... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00363215 CHEMBL148009 Bioactive SureCN5315520
CFAMM00363208 CHEMBL358541 Bioactive ethyl 1'-benzylspiro[3,4-dihydroisochromene-1,4'-piperidine]-3-carboxylate
CFAMM00363213 CHEMBL306182 Bioactive 8,8-dimethyl-3,3-diphenyl-1,4-dioxa-8-azoniaspiro[4.5]decan-2-one;iodide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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