CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5350
Family Name Gamma-aminobutyric acid receptor subunit pi and GABA theta subunit ligand tert-butyl 7-chloro-5-[(3R)-3-methylpiperazine-1-carbonyl]-4H-imidazo[1,5-a]quinoxaline-3-carboxylate family
No. of Seeds 24 No. of Other Members 0
Family Centroid CFAMM00363240 Functional Category Bioactive
Superfamily GABA theta subunit and Gamma-aminobutyric acid receptor subunit pi Binder Superfamily 5
Class Class 1259

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand Zopiclone Family 2 1
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Flumaz... 10 100
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 15 28
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 2 1
Gamma-aminobutyric acid receptor subunit alpha-5 and Gamma-ami... 1 2
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 9 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00363244 CHEMBL276143 Bioactive tert-butyl 7-chloro-5-[(3S,5R)-3,4,5-trimethylpiperazine-1-carbonyl]-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00363252 CHEMBL277110 Bioactive SureCN9078318
CFAMM00363255 CHEMBL278968 Bioactive tert-butyl 7-chloro-5-[(3S)-3-methylpiperazine-1-carbonyl]-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00363237 CHEMBL14914 Bioactive tert-butyl 7-chloro-5-[(3R,5R)-3,5-dimethylpiperazine-1-carbonyl]-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00363245 CHEMBL15140 Bioactive tert-butyl 7-chloro-5-(2,5-dimethylpiperazine-1-carbonyl)-4H-imidazo[1,5-a]quinoxaline-3-carboxylate;propanedioic acid
CFAMM00363243 CHEMBL276144 Bioactive butanoic acid;tert-butyl 7-chloro-5-[(3S,5R)-3,5-dimethylpiperazine-1-carbonyl]-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00363251 CHEMBL15143 Bioactive tert-butyl 7-chloro-5-(3,5-dimethylpiperazine-1-carbonyl)-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00363254 CHEMBL2079553 Bioactive tert-butyl 7-chloro-5-[(2S,3R)-2,3-dimethylpiperazine-1-carbonyl]-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00363236 CHEMBL2079608 Bioactive tert-butyl 7-chloro-5-[(2S,3S)-2,3-dimethylpiperazine-1-carbonyl]-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00363242 CHEMBL277782 Bioactive AGN-PC-0746YR
CFAMM00363250 CHEMBL15064 Bioactive tert-butyl 7-chloro-5-[(3R,5S)-3,5-dimethyl-4-methylsulfonylpiperazine-1-carbonyl]-4H-imidazo[1,5-a]quinoxaline-3-carboxylate;dichloromethane
CFAMM00363259 CHEMBL15180 Bioactive tert-butyl 7-chloro-5-(3-methylpiperazine-1-carbonyl)-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00363241 CHEMBL274915 Bioactive tert-butyl 7-chloro-5-(3,3,5,5-tetramethylpiperazine-1-carbonyl)-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00363249 CHEMBL14805 Bioactive AGN-PC-0746YQ
CFAMM00363258 CHEMBL279382 Bioactive tert-butyl 7-chloro-5-(3,3,4-trimethylpiperazine-1-carbonyl)-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00363240 CHEMBL14891 Bioactive tert-butyl 7-chloro-5-[(3R)-3-methylpiperazine-1-carbonyl]-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00363248 CHEMBL274982 Bioactive tert-butyl 7-chloro-5-(3,8-diazabicyclo[3.2.1]octane-3-carbonyl)-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00363257 CHEMBL277832 Bioactive tert-butyl 7-chloro-5-(piperazine-1-carbonyl)-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00363239 CHEMBL15319 Bioactive tert-butyl 7-chloro-5-[(3S,5R)-3,5-dimethyl-4-propan-2-ylpiperazine-1-carbonyl]-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00363247 CHEMBL14865 Bioactive AGN-PC-0746YN
CFAMM00363253 CHEMBL15107 Bioactive tert-butyl 7-chloro-5-(4-cyclopropylpiperazine-1-carbonyl)-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00363256 CHEMBL277383 Bioactive AGN-PC-00GD90
CFAMM00363238 CHEMBL352974 Bioactive tert-butyl 5-(2-chlorobenzoyl)-4H-imidazo[1,5-a]quinoxaline-3-carboxylate
CFAMM00363246 CHEMBL278439 Bioactive tert-butyl 5-[(3S,5R)-4-acetyl-3,5-dimethylpiperazine-1-carbonyl]-7-chloro-4H-imidazo[1,5-a]quinoxaline-3-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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