CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5354
Family Name 5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine receptor 1B ligand AGN-PC-00GBO5 family
No. of Seeds 7 No. of Other Members 4
Family Centroid CFAMM00363271 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine receptor 1D Binder Superfamily
Class Class 860

Cousin Family NamesSeedsMembers
Metabotropic glutamate receptor 1 Ligand PF-1913539 Family 130 817
Adenosine receptor A2a Ligand BIIB014 Family 26 92
Serine/threonine-protein kinase mTOR Inhibitor INK128 Family 2 15
Adenosine receptor A1 and Adenosine receptor A2a Ligand CGS-15... 24 47
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 3 44
Mitogen-activated protein kinase 14 Inhibitor CP-808844 Family 39 43
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-(fur... 7 15
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Dipeptidyl peptidase 8 and Dipeptidyl peptidase 9 inhibitor Su... 3 1
Survival motor neuron protein and Neuropeptide S receptor liga... 1 2
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 1
Adenosine receptor A2a ligand 2-(furan-2-yl)-7-[3-[(4-phenylpi... 11 2
Adenosine receptor A2a ligand 7-(3,4-dimethoxyphenyl)-2-(furan... 6 1
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 9 5
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 0
Growth hormone secretagogue receptor type 1 ligand SureCN36800... 14 42
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 6
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 1
Adenosine receptor A2a and Adenosine receptor A1 ligand 5-[(7S... 6 1
G1/S-specific cyclin-E1 and Cyclin-dependent kinase 2 inhibito... 1 4
Adenosine receptor A2a ligand 3-[(2-bromophenyl)methyl]-8-(fur... 2 0
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 25 5
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 29 1
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 1
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 1 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Adenosine receptor A2a ligand SureCN8368237 family 1 0
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 2
Adenosine receptor A3 and Adenosine receptor A1 ligand AGN-PC-... 2 2
Bombesin receptor subtype-3 ligand 2-[[(E)-furan-2-ylmethylide... 2 4
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 15 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00363272 CHEMBL434315 Bioactive N-(furan-2-ylmethyl)-N-methyl-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
CFAMM00363279 CHEMBL349185 Bioactive SureCN7474684
CFAMM00363271 CHEMBL357408 Bioactive AGN-PC-00GBO5
CFAMM00363270 CHEMBL162805 Bioactive SureCN7476283
CFAMM00363277 CHEMBL148085 Bioactive SureCN7479931
CFAMM00363269 CHEMBL349041 Bioactive SureCN7474581
CFAMM00363274 CHEMBL164111 Bioactive SureCN7475315

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26380 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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