CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM538
Family Name Aurora kinase A and Aurora kinase B inhibitor AGN-PC-00EQPZ family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00313015 Functional Category Bioactive
Superfamily Heat shock protein HSP 90-beta and Heat shock protein HSP 90-alpha Binder Superfamily
Class Class 1249

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Tyrosine-protein kinase SYK Inhibitor R788 Family 3 7
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Platelet-derived growth factor receptor beta and Platelet-deri... 2 19
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 10
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 1 3
ALK tyrosine kinase receptor and Insulin-like growth factor 1 ... 1 4
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 7 16
Focal adhesion kinase 1 inhibitor AGN-PC-00AVK6 family 1 1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 4 2
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 3 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00313015 CHEMBL1083152 Bioactive AGN-PC-00EQPZ
CFAMM00313014 CHEMBL1083151 Bioactive SureCN4159950
CFAMM00313013 CHEMBL1086088 Bioactive AGN-PC-00DCHI

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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