CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5392
Family Name Disintegrin and metalloproteinase domain-containing protein 17 inhibitor (2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-(naphthalen-1-ylmethoxy)butanediamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00363503 Functional Category Bioactive
Superfamily Disintegrin and Neutrophil collagenase Binder Superfamily
Class Class 1181

Cousin Family NamesSeedsMembers
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Disintegrin and metalloproteinase domain-containing protein 17... 8 7
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Cathepsin S inhibitor SureCN6857538 family 2 12
Neutrophil collagenase and Matrix metalloproteinase-9 inhibito... 6 1
Endothelin-converting enzyme 1 and Cathepsin D inhibitor N-[(2... 6 2
Proteasome subunit beta type-5 and Proteasome subunit beta typ... 1 0
Neutrophil collagenase and Matrix metalloproteinase-9 inhibito... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00363504 CHEMBL344312 Bioactive (2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-(naphthalen-2-ylmethoxy)butanediamide
CFAMM00363503 CHEMBL148373 Bioactive (2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-(naphthalen-1-ylmethoxy)butanediamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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