CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5454
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor (2S)-2-[[(2S)-5-[[(2R)-2-amino-3-sulfanylpropanoyl]amino]-2-(thiophen-2-ylmethyl)pentanoyl]amino]-4-methylsulfanylbutanoic acid family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00363934 Functional Category Bioactive
Superfamily Angiotensin-converting enzyme Inhibitor Temocapril Superfamily
Class Class 745

Cousin Family NamesSeedsMembers
Penicillin binding protein inhibitor β-lactam aminopenicillin ... 12 359
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 7 54
Angiotensin-converting enzyme Inhibitor Temocapril Family 4 15
Angiotensin-converting enzyme and Neprilysin Inhibitor M100,24... 18 60
Neprilysin Inhibitor Thiorphan Family 41 68
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Gamma-g... 2 1
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-154957 Family 2 3
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Endothelin-converting enzyme 1 inhibitor (2S)-2-[[2-[(3-bromop... 1 0
Papain and Cathepsin S inhibitor dipeptide-derived nitrile, 20... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00363935 CHEMBL148911 Bioactive (2S)-2-[[1-[[(2S)-3-methyl-2-sulfanylbutanoyl]amino]cyclopentanecarbonyl]amino]-3-thiophen-3-ylpropanoic acid
CFAMM00363934 CHEMBL316831 Bioactive (2S)-2-[[(2S)-5-[[(2R)-2-amino-3-sulfanylpropanoyl]amino]-2-(thiophen-2-ylmethyl)pentanoyl]amino]-4-methylsulfanylbutanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27521 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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