CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Smoothened homolog inhibitor SureCN1091073 family
No. of Seeds 14 No. of Other Members 22
Family Centroid CFAMM00313123 Functional Category Bioactive
Superfamily Vascular endothelial growth factor receptor 2 Ligand 4-(4-p-tolylamino-phthalazin-1-yl)-benzamide Superfamily
Class Class 1152

Cousin Family NamesSeedsMembers
Smoothened homolog Inhibitor LY2940680 Family 3 18
Triple reuptake Inhibitor BMS-820836 Family 2 7
Vascular endothelial growth factor receptor 2 Ligand 4-(4-p-to... 3 7
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Smoothened homolog inhibitor SureCN1090957 family 1 2
Smoothened homolog inhibitor SureCN1091571 family 2 2
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... 3 7
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 10 0
Acyl-CoA desaturase 1 and Acyl-CoA desaturase inhibitor SureCN... 5 15
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Acyl-CoA desaturase 1 and Acyl-CoA desaturase inhibitor AGN-PC... 7 7
Acetylcholinesterase inhibitor 1-[3-[6-[2-(1-benzylpiperidin-4... 1 0
Acyl-CoA desaturase 1 and Acyl-CoA desaturase inhibitor N-(1H-... 1 0


External ID

Functional Category

Molecule Name

CFAMM00313119 CHEMBL1086048 Bioactive SureCN1091648
CFAMM00313111 CHEMBL1084835 Bioactive SureCN1090765
CFAMM00313104 CHEMBL1084730 Bioactive [(3R)-4-[4-(4-cyclopropylphenyl)phthalazin-1-yl]-3-methylpiperazin-1-yl]-phenylmethanone
CFAMM00313110 CHEMBL1084837 Bioactive AGN-PC-07ZGWV
CFAMM00313124 CHEMBL1083285 Bioactive SureCN1091425
CFAMM00313103 CHEMBL1084731 Bioactive SureCN1091174
CFAMM00313123 CHEMBL1083284 Bioactive SureCN1091073
CFAMM00313102 CHEMBL1084736 Bioactive SureCN1091512
CFAMM00313128 CHEMBL1083915 Bioactive SureCN1090253
CFAMM00313107 CHEMBL1084738 Bioactive SureCN1090951
CFAMM00313121 CHEMBL1086045 Bioactive SureCN1091112
CFAMM00313127 CHEMBL1083914 Bioactive SureCN1091375
CFAMM00313120 CHEMBL1085503 Bioactive STK263817
CFAMM00313106 CHEMBL1086467 Bioactive SureCN1089469

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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