CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5470
Family Name Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibitor Indenopyrazole 8c family
No. of Seeds 1 No. of Other Members 29
Family Centroid CFAMM00364036 Functional Category Bioactive
Superfamily Leucine-rich repeat serine/threonine-protein kinase 2 and Orexin receptor type 1 Binder Superfamily
Class Class 208

Cousin Family NamesSeedsMembers
Hepatocyte growth factor receptor Ligand MK-8033 Family 19 42
G1/S-specific cyclin-E2 and G1/S-specific cyclin-E1 inhibitor ... 1 8
5-hydroxytryptamine receptor 3A ligand SureCN8035577 family 5 4
Hepatocyte growth factor receptor ligand 9-[[3-methoxypropyl(m... 17 2
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 2 18
Rho-associated protein kinase 2 and Rho-associated protein kin... 2 6
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 1
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
Serine/threonine-protein kinase Chk1 inhibitor 5-[(2S)-3-amino... 4 6
5-hydroxytryptamine receptor 1B ligand 8-(3,5-dimethyl-1H-pyra... 1 0
G1/S-specific cyclin-E2 and G1/S-specific cyclin-E1 inhibitor ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00364036 CHEMBL148995 Bioactive Indenopyrazole 8c

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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