CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM55
Family Name Corticotropin-releasing factor receptor 1 ligand 4-N-(2-bromo-4-propan-2-ylphenyl)-4-N-ethyl-6-methyl-2-N,2-N-bis(prop-2-enyl)-1,3,5-triazine-2,4-diamine family
No. of Seeds 9 No. of Other Members 48
Family Centroid CFAMM00306414 Functional Category Bioactive
Superfamily Corticotropin-releasing factor receptor 1 Binder Superfamily
Class Class 3062

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Pyrimethamine Family 10 145
Corticotropin-releasing factor receptor 1 Ligand CP-154526 Family 9 29
Corticotropin-releasing factor receptor 1 Ligand CRA1000 Family 4 39
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 32
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Epidermal growth factor receptor Ligand N*4*-(3-bromo-phenyl)-... 7 11
Epidermal growth factor receptor Ligand Benzo[g]quinazolin-4-y... 5 3
Epidermal growth factor receptor Ligand (3-bromo-phenyl)-quina... 7 5
Cathepsin K Inhibitor 4-phenyl-6-propylpyrimidine-2-carbonitri... 6 10
Macrophage migration inhibitory factor Inhibitor 4-iodo-6-phen... 5 4
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
Glycogen synthase kinase-3 beta Inhibitor 4-(5-bromo-1h-indol-... 7 18
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 9 16
Metabotropic glutamate receptor 5 Ligand 2-(3-bromophenyl)-7-m... 3 1
Corticotropin-releasing factor receptor 1 ligand N-(2-bromo-4-... 5 0
Adenosine kinase inhibitor abt-702 family 14 1
Corticotropin-releasing factor receptor 1 ligand AGN-PC-01ZUJC... 2 1
Corticotropin-releasing factor receptor 1 ligand 3-(2-bromo-4-... 13 34
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 2
Corticotropin-releasing factor receptor 1 ligand AGN-PC-00GBP0... 3 1
Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4-... 15 3
Corticotropin-releasing factor receptor 1 ligand 4-N-[2-bromo-... 3 11
Corticotropin-releasing factor receptor 1 ligand 3-(2,4-dibrom... 2 0
Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4-... 5 2
Toll-like receptor 7 ligand 6-amino-2-(butylamino)-9-[[4-(dime... 5 4
Corticotropin-releasing factor receptor 1 ligand 7-[bis(2-meth... 3 0
Corticotropin-releasing factor receptor 1 ligand SureCN8181501... 4 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 7
Corticotropin-releasing factor receptor 1 ligand AGN-PC-008HTV... 2 1
Growth hormone secretagogue receptor type 1 ligand AGN-PC-0760... 4 0
Adenosine kinase inhibitor 5-(4-bromophenyl)-6-[2-[4-(dimethyl... 1 0
Adenosine kinase inhibitor AGN-PC-074DKZ family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00306375 CHEMBL168844 Bioactive 4-N-(2-bromo-4-propan-2-ylphenyl)-4-N-ethyl-6-methyl-2-N,2-N-dipropyl-1,3,5-triazine-2,4-diamine
CFAMM00306414 CHEMBL424555 Bioactive 4-N-(2-bromo-4-propan-2-ylphenyl)-4-N-ethyl-6-methyl-2-N,2-N-bis(prop-2-enyl)-1,3,5-triazine-2,4-diamine
CFAMM00306394 CHEMBL10082 Bioactive SureCN8211399
CFAMM00306359 CHEMBL166388 Bioactive 4-N-(2-bromo-4-propan-2-ylphenyl)-2-N-butyl-2-N,4-N-diethyl-6-methyl-1,3,5-triazine-2,4-diamine
CFAMM00306405 CHEMBL268993 Bioactive 2-N-(2-bromo-4-propan-2-ylphenyl)-4-N-(cyclopropylmethyl)-2-N-ethyl-6-methyl-4-N-propylpyrimidine-2,4-diamine
CFAMM00306411 CHEMBL10203 Bioactive 2-N-(2-bromo-4-propan-2-ylphenyl)-2-N-ethyl-6-methyl-4-N,4-N-dipropylpyrimidine-2,4-diamine
CFAMM00306403 CHEMBL167407 Bioactive N-(2-bromo-4-propan-2-ylphenyl)-N-ethyl-4-methyl-6-pentan-3-ylpyrimidin-2-amine
CFAMM00306370 CHEMBL166345 Bioactive 4-N-(2-bromo-4-propan-2-ylphenyl)-2-N-cyclopropyl-4-N-ethyl-6-methyl-2-N-prop-2-enyl-1,3,5-triazine-2,4-diamine
CFAMM00306409 CHEMBL353877 Bioactive AGN-PC-00GCQA

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543