CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5542
Family Name Substance-P receptor ligand 1-benzyl-5-(3,4-dichlorophenyl)-5-[2-(3-morpholin-4-ylazetidin-1-yl)ethyl]piperidin-2-one family
No. of Seeds 9 No. of Other Members 0
Family Centroid CFAMM00364573 Functional Category Bioactive
Superfamily Neuromedin-K receptor Ligand Osanetant Superfamily
Class Class 908

Cousin Family NamesSeedsMembers
Amine oxidase [flavin-containing] A Inhibitor Moclobemide Family 5 255
Neuromedin-K receptor Ligand Osanetant Family 38 192
Substance-K receptor and Substance-P receptor Ligand DNK-333 F... 15 95
Tumor necrosis factor Inhibitor Talactoferrin Alfa Family 26 131
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 10 52
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Substance-P receptor ligand 4-[1-[2-[1-(cyclopropylmethyl)-3-(... 10 6
Substance-K receptor ligand (5S)-1-(2-cyclopropylethyl)-5-(3,4... 10 0
Substance-P receptor ligand 1-benzyl-5-(3,4-dichlorophenyl)-5-... 5 0
Substance-P receptor ligand 1-benzyl-5-(3,4-dichlorophenyl)-5-... 3 0
Substance-P receptor ligand 1-benzyl-5-(3,4-dichlorophenyl)-5-... 2 0
Substance-P receptor ligand 1-(cyclohexylmethyl)-5-(3,4-dichlo... 8 1
Neuromedin-K receptor ligand (1S,2R)-1-(3,4-dichlorophenyl)-N-... 8 0
Prothrombin inhibitor AGN-PC-09QJ23 family 2 5
Prostaglandin D2 receptor 2 ligand SureCN4942606 family 2 8
Substance-K receptor ligand AGN-PC-0759BS family 3 6
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 6 0
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[[2-(2,4-dic... 4 9
Substance-K receptor ligand SureCN3083325 family 4 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 6 3
Substance-P receptor ligand 1-benzyl-5-(3,4-dichlorophenyl)-5-... 1 1
Free fatty acid receptor 1 ligand (3R,4R)-3-(3,4-dichloropheny... 1 0
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[(3,4-dichlo... 1 0
Neuromedin-K receptor and Substance-K receptor ligand AGN-PC-0... 2 0
Putative Bioactive [3-[benzoyl(hydroxy)amino]-1-(3,4-dichlorop... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00364576 CHEMBL151155 Bioactive 4-[1-[2-[1-benzyl-3-(3,4-dichlorophenyl)-6-oxopiperidin-3-yl]ethyl]azetidin-3-yl]morpholin-3-one
CFAMM00364575 CHEMBL71644 Bioactive AGN-PC-074GHR
CFAMM00364574 CHEMBL71647 Bioactive SureCN493662
CFAMM00364580 CHEMBL149690 Bioactive 5-(3,4-dichlorophenyl)-1-[(2-methylphenyl)methyl]-5-[2-(3-morpholin-4-ylazetidin-1-yl)ethyl]piperidin-2-one
CFAMM00364573 CHEMBL348653 Bioactive 1-benzyl-5-(3,4-dichlorophenyl)-5-[2-(3-morpholin-4-ylazetidin-1-yl)ethyl]piperidin-2-one
CFAMM00364579 CHEMBL358418 Bioactive 1-benzyl-5-(3,4-dichlorophenyl)-5-[2-[3-(1,4-oxazepan-4-yl)azetidin-1-yl]ethyl]piperidin-2-one
CFAMM00364572 CHEMBL150644 Bioactive 5-(3,4-dichlorophenyl)-1-[(4-methylphenyl)methyl]-5-[2-(3-morpholin-4-ylazetidin-1-yl)ethyl]piperidin-2-one
CFAMM00364578 CHEMBL347284 Bioactive 5-(3,4-dichlorophenyl)-1-[(3-methylphenyl)methyl]-5-[2-(3-morpholin-4-ylazetidin-1-yl)ethyl]piperidin-2-one
CFAMM00364577 CHEMBL69889 Bioactive AGN-PC-074GE1

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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