CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5554
Family Name DNA-(apurinic or apyrimidinic site) lyase and Menin inhibitor CHEMBL1498445 family
No. of Seeds 1 No. of Other Members 6
Family Centroid CFAMM00364678 Functional Category Bioactive
Superfamily Carbonic anhydrase 2 Inhibitor AL5927 Superfamily
Class Class 1931

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Dulo... 8 6
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Cathepsin G and Neutrophil elastase Inhibitor Dermolastin Family 1 15
D(2) dopamine receptor Ligand N-0923 Family 6 41
D(3) dopamine receptor Ligand U-99194A Family 7 33
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
Tumor necrosis factor Inhibitor Y-39041 Family 9 51
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand (r)-1-(2-methoxyphenethyl)-2-meth... 10 27
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 7 0
Leukotriene A-4 hydrolase inhibitor SureCN13809114 family 2 7
Leukotriene A-4 hydrolase inhibitor SureCN2108222 family 3 9
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 13
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 0
Orexin receptor type 2 and Orexin receptor type 1 ligand (2S)-... 2 0
Squalene monooxygenase inhibitor 4-bromo-N-[2-[3-[[[(E)-6,6-di... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00364683 CHEMBL542049 Bioactive SureCN9075484

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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