CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM557
Family Name Histamine H3 receptor and Potassium voltage-gated channel subfamily H member 2 ligand SureCN3457130 family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00313232 Functional Category Bioactive with Natural Product
Superfamily Mu-type opioid receptor and Delta-type opioid receptor Binder Superfamily 6
Class Class 2081

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Phospholipase A2 Inhibitor Quinacrine Family 13 95
Apricoxib family 8 77
Nicotinic acetylcholine receptor alpha2 / alpha3 Ligand Ibogai... 3 21
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
Oestrogen receptor and Estrogen receptor beta Ligand Pipendoxi... 11 48
D(2) dopamine receptor Ligand SLV-314 Family 19 69
5-hydroxytryptamine receptor 2A and Alpha-2A adrenergic recept... 4 29
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(2-methyl... 7 27
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(1,5-naph... 4 20
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Corticotropin-releasing factor receptor 1 ligand AGN-PC-074YQD... 1 5
Neuropeptide Y receptor type 1 ligand SureCN7959923 family 1 6
Melanin-concentrating hormone receptor 1 and Cytochrome P450 3... 8 2
Hypoxia-inducible factor 1-alpha and Lethal factor inhibitor C... 1 1
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(2-... 3 3
Coagulation factor X and Anionic trypsin-2 inhibitor AGN-PC-07... 1 1
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 2 13
5-hydroxytryptamine receptor 6 ligand 1-[9-(benzenesulfonyl)-6... 11 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 16 19
Sodium-dependent serotonin transporter inhibitor SureCN7536104... 6 2
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 3 0
Substance-P receptor ligand 1-[4-(2-methoxyphenyl)piperazin-1-... 11 12
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 5
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 4 4
Corticotropin-releasing factor receptor 1 ligand 3-ethyl-1-(2-... 5 15
C5a anaphylatoxin chemotactic receptor 1 ligand 2-(2,6-diethyl... 3 5
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
Gonadotropin-releasing hormone receptor ligand 2-[2-(4-methoxy... 1 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 23 5
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00313232 CHEMBL1083448 Bioactive SureCN3457130

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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