CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM559
Family Name Vasopressin V2 receptor and Vasopressin V1a receptor ligand [2-chloro-4-(2,3-dichloro-4-quinolin-8-ylphenyl)phenyl]-[(1R,5S)-3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl]methanone family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00313240 Functional Category Bioactive
Superfamily ABC294640 Superfamily
Class Class 913

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Histamine H1 receptor ligand tricyclic antidepressant Loratadi... 5 163
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
D(3) dopamine receptor Ligand SB-277011 Family 13 178
D(4) dopamine receptor Ligand SPI-376 Family 7 84
Substance-P receptor Ligand TAK-637 Family 18 63
ABC294640 family 5 75
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Cannabinoid receptor 2 Ligand JWH-204 Family 6 10
Cannabinoid receptor 2 Ligand JWH-249 Family 7 13
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 24 50
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 37 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-2... 8 1
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Endothelin B receptor Ligand IRL-2500 Family 34 87
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Substance-P receptor ligand AGN-PC-01ZIXQ family 13 42
RAC-alpha serine/threonine-protein kinase and Cyclin-dependent... 3 7
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 6 9
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 1 1
Acetylcholinesterase inhibitor CHEMBL1651131 family 6 9
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
C-C chemokine receptor type 3 and Probable C-C chemokine recep... 2 4
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6R... 2 2
Glycogen synthase kinase-3 beta inhibitor 7-(6-chloropyridin-2... 2 3
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Melanin-concentrating hormone receptor 1 and 5-hydroxytryptami... 1 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 2 3
Histamine H1 receptor and Alpha-1B adrenergic receptor ligand ... 8 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 8 6
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... 22 3
Gonadotropin-releasing hormone receptor ligand 1-adamantyl-[2-... 3 1
C-C chemokine receptor type 2 ligand SureCN5946889 family 2 6
Acetylcholinesterase inhibitor N-[6-[4-[(6-chloro-1,2,3,4-tetr... 9 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 2
Substance-K receptor and Substance-P receptor ligand 3,5-dichl... 3 0
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... 2 0
Melanin-concentrating hormone receptor 1 and Potassium voltage... 1 1
KiSS-1 receptor ligand SureCN5132924 family 2 4
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 1 1
Macrophage colony-stimulating factor 1 receptor ligand AGN-PC-... 3 0
Cannabinoid receptor 1 ligand [6-bromo-2-methyl-1-(2-morpholin... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00313240 CHEMBL1083479 Bioactive [2-chloro-4-(2,3-dichloro-4-quinolin-8-ylphenyl)phenyl]-[(1R,5S)-3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl]methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26223 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543