CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5608
Family Name Adenosine kinase inhibitor SureCN8183719 family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00257105 Functional Category Bioactive
Superfamily Corticotropin-releasing factor receptor 1 Ligand CRA1000 Superfamily
Class Class 1493

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor SNS-314 Family 2 75
Transient receptor potential cation channel subfamily V member... 15 457
5-hydroxytryptamine receptor 3A Ligand DDP-225 Family 1 7
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
TGF-beta receptor type-1 Ligand 4-pyridin-2-yl-5-quinolin-4-yl... 4 23
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 6 64
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-ethy... 2 2
Histamine H4 receptor Ligand A-943931 Family 14 11
Glycogen synthase kinase-3 beta Inhibitor 4-(5-bromo-1h-indol-... 7 18
Prostaglandin G/H synthase 2 Inhibitor GW-637185X Family 27 48
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 22
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Aurora kinase B and Aurora kinase A inhibitor AGN-PC-07ZBLC fa... 3 8
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 8 6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 1
Vascular endothelial growth factor receptor 2 and Mast/stem ce... 10 27
Mitogen-activated protein kinase 14 and LIM domain kinase 1 in... 4 19
DNA-(apurinic or apyrimidinic site) lyase and Neuropeptide S r... 1 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 10
Epidermal growth factor receptor ligand AGN-PC-07C2E2 family 7 6
Cell division cycle 7-related protein kinase inhibitor AGN-PC-... 6 6
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 5 27
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-0A9RCZ family 7 7
Histamine H4 receptor ligand 8-chloro-4-[(3R)-3-(methylamino)p... 3 10
Histamine H4 receptor ligand 8-bromo-4-(4-methylpiperazin-1-yl... 2 1
Vascular endothelial growth factor receptor 2 and Platelet-der... 3 3
Serine/threonine-protein kinase Chk1 inhibitor 5-[5-(1-methylp... 3 2
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(1,4-di... 3 3
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 7
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 3 6
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 3 0
Prostaglandin G/H synthase 2 inhibitor 4-N,4-N-diethyl-2-(4-me... 5 1
Epidermal growth factor receptor ligand AGN-PC-076GWD family 2 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 2
Epidermal growth factor receptor and Vascular endothelial grow... 7 0
Adenosine kinase inhibitor AGN-PC-075RO3 family 1 0
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor AGN-P... 1 0
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck ligand... 1 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 5 0
Adenosine kinase inhibitor AGN-PC-074DKZ family 1 0
Vascular endothelial growth factor receptor 2 and Insulin rece... 2 0
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 5 1
Epidermal growth factor receptor ligand AGN-PC-075SGM family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00364867 CHEMBL191309 Bioactive 6-[(3-bromophenyl)methyl]-7-thiophen-2-ylpyrido[2,3-d]pyrimidin-4-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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