CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5636
Family Name Integrin beta-3 and Integrin alpha-V inhibitor SureCN6359092 family
No. of Seeds 9 No. of Other Members 5
Family Centroid CFAMM00365065 Functional Category Bioactive
Superfamily Integrin alpha-V and Integrin beta-3 Binder Superfamily 2
Class Class 898

Cousin Family NamesSeedsMembers
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
Integrin beta-3 Inhibitor Elarofiban Family 28 45
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-03RR5Q f... 3 2
Integrin beta-3 and Integrin alpha-V inhibitor methyl (3S)-3-(... 12 13
Integrin beta-3 and Integrin alpha-V inhibitor SureCN547914 fa... 8 32
Integrin alpha-V and Integrin beta-5 inhibitor SureCN6563167 f... 2 10
Integrin beta-3 and Integrin alpha-V inhibitor SureCN3888804 f... 11 13
Integrin beta-3 and Integrin alpha-V inhibitor (3R)-3-quinolin... 6 8
Serine/threonine-protein kinase Chk1 inhibitor SureCN3070314 f... 16 32
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-[[2-[6-m... 13 12
Carboxypeptidase B2 and Carboxypeptidase B inhibitor 3-(6-amin... 5 10
Integrin beta-3 and Integrin alpha-IIb inhibitor 3-[[1-(3-pipe... 3 0
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 3 1
B1 bradykinin receptor ligand AGN-PC-005XAO family 3 17
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-2-(benzene... 3 2
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[5-methy... 4 5
Integrin beta-3 and Integrin alpha-V inhibitor SureCN8335217 f... 2 1
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-00BBPN f... 2 3
Integrin beta-3 and Integrin alpha-V inhibitor SureCN2833591 f... 4 6
Integrin beta-3 and Integrin alpha-V inhibitor SureCN2842307 f... 4 0
Succinate receptor 1 ligand N-[[4-(3-methylphenyl)phenyl]methy... 2 14
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 7 6
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 0
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-00IW9E f... 3 0
Integrin alpha-V and Integrin beta-6 inhibitor 3-[[2-[4-[(4-me... 4 3
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(3-fluor... 10 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (3S)-3-[[3-(2... 4 2
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-074ASZ f... 5 0
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-[[2-[4-(... 3 0
Tryptophan 5-hydroxylase 1 inhibitor (2S)-2-amino-3-[4-[4-amin... 1 23
Integrin beta-3 and Integrin alpha-IIb inhibitor (3S)-3-[[2-[(... 3 1
Integrin beta-1 and Integrin alpha-5 inhibitor 2-[(2,6-dimethy... 9 1
Sigma non-opioid intracellular receptor 1 ligand methyl 1-(4-c... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00365067 CHEMBL150678 Bioactive AGN-PC-075RTQ
CFAMM00365066 CHEMBL420768 Bioactive (3S)-3-pyrimidin-5-yl-3-[5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoylamino]propanoic acid
CFAMM00365065 CHEMBL186552 Bioactive SureCN6359092
CFAMM00365071 CHEMBL361936 Bioactive (3S)-3-(2-propan-2-ylpyrimidin-5-yl)-9-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)nonanoic acid
CFAMM00365063 CHEMBL187176 Bioactive SureCN2927647
CFAMM00365062 CHEMBL187014 Bioactive (3R)-4-[1-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propanoyl]piperidin-4-yl]-3-(5,6,7,8-tetrahydroquinolin-3-yl)butanoic acid
CFAMM00365068 CHEMBL186126 Bioactive SureCN6536413
CFAMM00365061 CHEMBL187289 Bioactive SureCN6106842

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27398 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543