CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM564
Family Name Histamine H3 receptor and Potassium voltage-gated channel subfamily H member 2 ligand SureCN1574546 family
No. of Seeds 6 No. of Other Members 20
Family Centroid CFAMM00313281 Functional Category Bioactive with Natural Product
Superfamily Acetylcholinesterase and Histamine H3 receptor Binder Superfamily
Class Class 3184

Cousin Family NamesSeedsMembers
Platelet-derived growth factor receptor alpha and Platelet-der... 5 48
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 16
Metabotropic glutamate receptor 5 Ligand 2-methyl-4-(pyridin-3... 10 35
TGF-beta receptor type-1 Ligand 4-pyridin-2-yl-5-quinolin-4-yl... 4 23
Aldose reductase Inhibitor Lidorestat Family 16 27
Mitogen-activated protein kinase 14 Inhibitor 4-(2-ethyl-4-m-t... 14 41
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(thiophen... 9 66
Cyclin-dependent kinase 5 Inhibitor 1-phenyl-3-(2-(pyridin-4-y... 3 53
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-264... 6 32
Histamine H3 receptor Ligand ST-1025 Family 2 22
Translocator protein Inhibitor 5-phenyl-6-thia-10b-aza-benzo[e... 1 2
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Reverse transcriptase Inhibitor 1-benzothiazol-2-yl-3-phenethy... 2 19
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-(2,6... 5 9
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 14
5-hydroxytryptamine receptor 6 ligand CHEMBL1950756 family 8 8
Neuropeptide Y receptor type 5 ligand N-[[(1S,5R)-3-(1-phenyle... 5 1
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 2 4
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 3 7
5-hydroxytryptamine receptor 2A and Alpha-1B adrenergic recept... 8 6
Sigma non-opioid intracellular receptor 1 ligand SureCN7434677... 1 0
Amyloid beta A4 protein and Luciferin 4-monooxygenase inhibito... 11 46
D(4) dopamine receptor ligand SureCN8706945 family 4 10
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 3
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 1 1
5-hydroxytryptamine receptor 1A and Alpha-2C adrenergic recept... 2 2
Epidermal growth factor receptor and Vascular endothelial grow... 14 19
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 3 4
Amyloid beta A4 protein inhibitor SureCN2465837 family 4 2
Protein kinase C theta type and Protein kinase C delta type in... 4 5
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 4 1
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
Vascular endothelial growth factor receptor 2 and Vascular end... 1 1
D(2) dopamine receptor and Alpha-1A adrenergic receptor ligand... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00313281 CHEMBL1084878 Bioactive SureCN1574546
CFAMM00313280 CHEMBL1085592 Bioactive SureCN1574289
CFAMM00313269 CHEMBL1086072 Bioactive SureCN1574307
CFAMM00313301 CHEMBL1085866 Bioactive SureCN1574345
CFAMM00313278 CHEMBL1086292 Bioactive SureCN1574313
CFAMM00313297 CHEMBL1083562 Bioactive SureCN3458820

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26197 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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