CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5651
Family Name Vascular endothelial growth factor receptor 2 and Vascular endothelial growth factor receptor 1 ligand 4-anilinocinnoline deriv. 18 family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00365165 Functional Category Bioactive
Superfamily Vascular endothelial growth factor receptor 2 and Vascular endothelial growth factor receptor 1 ligand 4-anilinocinnoline deriv. 18 Superfamily
Class Class 4303

Cousin Family NamesSeedsMembers
DNA Binder Primaquine Family 3 245
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
Epidermal growth factor receptor and Receptor tyrosine-protein... 16 89
Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
Abelson tyrosine-protein kinase 2 and Proto-oncogene tyrosine-... 25 40
Abelson tyrosine-protein kinase 2 and Proto-oncogene tyrosine-... 67 130
Tivozanib family 4 6
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Platelet-derived growth factor receptor beta and Epidermal gro... 3 7
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Proto-oncogene tyrosine-protein kinase Src inhibitor N-(2,4-di... 3 0
Dual specificity mitogen-activated protein kinase kinase 1 inh... 5 7
Epidermal growth factor receptor ligand N-[4-(3-chloro-4-fluor... 6 47
Proto-oncogene tyrosine-protein kinase Src inhibitor SureCN525... 8 8
Proto-oncogene tyrosine-protein kinase Src inhibitor AC1NS5MA ... 3 4
Proto-oncogene tyrosine-protein kinase Src inhibitor AC1NS94Q ... 6 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 8 1
Platelet-derived growth factor receptor alpha and Mast/stem ce... 2 2
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN4... 9 2
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 11 7
Vascular endothelial growth factor receptor 2 and Tyrosine-pro... 4 0
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 1 0
Macrophage colony-stimulating factor 1 receptor ligand 4-(3-ch... 5 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00365168 CHEMBL433936 Bioactive Anilinoquinoline deriv. 16
CFAMM00365165 CHEMBL150826 Bioactive 4-anilinocinnoline deriv. 18
CFAMM00365164 CHEMBL150825 Bioactive 4-anilinocinnoline deriv. 19

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48707 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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