CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5693
Family Name Sigma non-opioid intracellular receptor 1 ligand 2-(3-bromophenyl)-N-methyl-N-(2-pyrrolidin-1-ylethyl)ethanamine family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00365362 Functional Category Bioactive
Superfamily Sigma non-opioid intracellular receptor 1 Binder Superfamily 3
Class Class 346

Cousin Family NamesSeedsMembers
Beta adrenergic receptor Ligand Bretylium Family 3 11
Sodium-dependent noradrenaline transporter and Sodium-dependen... 4 2
Neuronal acetylcholine receptor subunit alpha-9 ligand 3-(4-br... 2 2
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-003L8Y... 2 4
D(2) dopamine receptor ligand AGN-PC-041NNJ family 1 2


External ID

Functional Category

Molecule Name

CFAMM00365362 CHEMBL151136 Bioactive 2-(3-bromophenyl)-N-methyl-N-(2-pyrrolidin-1-ylethyl)ethanamine
CFAMM00365364 CHEMBL346153 Bioactive 2-(4-bromophenyl)-N-methyl-N-(2-pyrrolidin-1-ylethyl)ethanamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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