CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5709
Family Name 5-hydroxytryptamine receptor 6 ligand 1-(4-methoxy-3-piperazin-1-ylphenyl)sulfonyl-2,2-dimethyl-3H-indole family
No. of Seeds 6 No. of Other Members 3
Family Centroid CFAMM00365507 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 Ligand SB-357134 Superfamily
Class Class 1633

Cousin Family NamesSeedsMembers
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
5-hydroxytryptamine receptor 6 Ligand Sb 258585 Family 11 121
5-hydroxytryptamine receptor 6 Ligand SB-357134 Family 13 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 20 33
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Pyruvate kinase PKLR and Pyruvate kinase PKM inhibitor AGN-PC-... 1 1
5-hydroxytryptamine receptor 6 ligand N-(3,5-dichlorophenyl)-4... 7 2
Alpha-2A adrenergic receptor and 5-hydroxytryptamine receptor ... 7 10
Bifunctional epoxide hydrolase 2 inhibitor SureCN2729784 family 3 9
5-hydroxytryptamine receptor 6 ligand 8-chloro-2-(4-methoxy-3-... 4 1
5-hydroxytryptamine receptor 6 ligand 6-bromo-1-(4-methoxy-3-p... 2 0
5-hydroxytryptamine receptor 6 ligand AGN-PC-0BRZ7B family 9 2
5-hydroxytryptamine receptor 1A ligand AGN-PC-0A9RI2 family 2 2
Sigma non-opioid intracellular receptor 1 ligand N-[6-[[5-[3-(... 1 1
Neuropeptide Y receptor type 5 ligand N-[[4-[2-[7-(trifluorome... 1 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 14
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 10 1
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 5 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 1
Growth hormone secretagogue receptor type 1 ligand SureCN47965... 3 1
Growth hormone secretagogue receptor type 1 ligand SureCN47962... 8 0
Growth hormone secretagogue receptor type 1 ligand SureCN48020... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-met... 3 3
72 kDa type IV collagenase and Interstitial collagenase inhibi... 2 0
5-hydroxytryptamine receptor 6 ligand N-(3-bromo-2,5-dichlorop... 2 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 3 3
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00365503 CHEMBL157285 Bioactive 5-iodo-1-(4-methoxy-3-piperazin-1-ylphenyl)sulfonyl-2,3-dihydroindole
CFAMM00365509 CHEMBL154675 Bioactive 4-methoxy-3-piperazin-1-yl-N-(2-propan-2-ylphenyl)benzenesulfonamide
CFAMM00365507 CHEMBL151295 Bioactive 1-(4-methoxy-3-piperazin-1-ylphenyl)sulfonyl-2,2-dimethyl-3H-indole
CFAMM00365506 CHEMBL155234 Bioactive 1-(4-methoxy-3-piperazin-1-ylphenyl)sulfonyl-5-methyl-6-(trifluoromethyl)-2,3-dihydroindole
CFAMM00365505 CHEMBL156610 Bioactive 4-methoxy-N-[2-methoxy-5-(trifluoromethyl)phenyl]-3-piperazin-1-ylbenzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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