CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5710
Family Name Survival motor neuron protein and Retinal dehydrogenase 1 inhibitor CHEMBL1513076 family
No. of Seeds 1 No. of Other Members 11
Family Centroid CFAMM00365558 Functional Category Bioactive with Human Metabolite & Natural Product
Superfamily Glucocorticoid receptor Ligand GW685698X Superfamily
Class Class 987

Cousin Family NamesSeedsMembers
Retinoic acid receptor Ligand naphthoic acid derivative Adapal... 2 264
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
Estrogen receptor beta Ligand 2-(4-hydroxy-phenyl)benzofuran-5... 5 82
Kappa-type opioid receptor Ligand Salvinorin B Butoxymethyl Et... 38 215
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 56
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Arachidonate 15-lipoxygenase Inhibitor Igernellin Family 2 30
Bifunctional epoxide hydrolase 2 Inhibitor 13-(5-n-pentylfuran... 1 80
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Kappa-type opioid receptor Ligand 2-epi-2-thiosalvinorin B Family 6 7
Creatine kinase Inhibitor 5-(4'-benzoylbiphenyl-4-yl)-2-furoic... 2 66
Retinoic acid receptor RXR-alpha and Peroxisome proliferator-a... 3 17
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 78
Multidrug resistance protein 1 inhibitor CHEMBL394284 family 5 4
Furans Metabolite 2-Isopropyl-5-methylfuran Family 1 1
Furans Metabolite Perilla ketone Family 2 5
Furans Metabolite 2-Acetyl-3-methylfuran Family 1 3
Furans Metabolite Egomaketone Family 4 6
Prenol Lipids Metabolite Furanogermenone Family 2 2
Prenol Lipids Metabolite Ipomeamaronol Family 2 2
Sphydrofuran Derivative NP ZINC14591771 Family 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00365524 CHEMBL347411 Bioactive (2E,4E)-3-methyl-5-[2-[(E)-2-(2,6,6-trimethylcyclohexen-1-yl)ethenyl]furan-3-yl]penta-2,4-dienoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27397 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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