CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5715
Family Name Cysteinyl leukotriene receptor 1 ligand 3-[1-[3-[(7-chloroquinolin-2-yl)methoxy]phenyl]-3-[2-(dimethylcarbamoyl)phenyl]propyl]sulfanyl-2-methylpropanoic acid family
No. of Seeds 5 No. of Other Members 6
Family Centroid CFAMM00365589 Functional Category Bioactive
Superfamily Prostaglandin E synthase and Arachidonate 5-lipoxygenase Binder Superfamily
Class Class 1637

Cousin Family NamesSeedsMembers
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Arachidonate 5-lipoxygenase Inhibitor MK-591 Family 9 161
Arachidonate 5-lipoxygenase-activating protein Inhibitor AM103... 14 12
Leukotriene B4 receptor 1 Ligand SB-209247 Family 7 24
Cysteinyl leukotriene receptor 1 ligand SureCN9053715 family 2 11
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Arachidonate 5-lipoxygenase-activating protein inhibitor SureC... 8 1
Cytochrome P450 3A4 and Cytochrome P450 2D6 inhibitor SureCN16... 8 4
Arachidonate 5-lipoxygenase inhibitor SureCN6008522 family 1 6
Arachidonate 5-lipoxygenase-activating protein inhibitor 3-[5-... 1 0
Arachidonate 5-lipoxygenase-activating protein inhibitor AGN-P... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00365584 CHEMBL430147 Bioactive AGN-PC-02JSXV
CFAMM00365583 CHEMBL15485 Bioactive 3-[1-[3-[(7-chloroquinolin-2-yl)methoxy]phenyl]-6-(dimethylamino)-4-methyl-6-oxohexyl]sulfanylpropanoic acid
CFAMM00365589 CHEMBL15132 Bioactive 3-[1-[3-[(7-chloroquinolin-2-yl)methoxy]phenyl]-3-[2-(dimethylcarbamoyl)phenyl]propyl]sulfanyl-2-methylpropanoic acid
CFAMM00365582 CHEMBL279773 Bioactive AGN-PC-02JSVQ
CFAMM00365587 CHEMBL276584 Bioactive 3-[1-[3-[(7-chloroquinolin-2-yl)methoxy]phenyl]-3-[2-[hydroxymethyl(methyl)carbamoyl]phenyl]propyl]sulfanyl-2-methylpropanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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