CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM573
Family Name Rho-associated protein kinase 2 inhibitor N-(7-chloro-1-oxo-2H-isoquinolin-6-yl)-4-(3-methoxyphenyl)pyrrolidine-3-carboxamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00313340 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Binder Superfamily 2
Class Class 1458

Cousin Family NamesSeedsMembers
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Potassium voltage-gated channel subfamily H member 2 and Melan... 2 12
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 10 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00313341 CHEMBL1084800 Bioactive N-(7-chloro-1-oxo-2H-isoquinolin-6-yl)-4-[3-(trifluoromethoxy)phenyl]pyrrolidine-3-carboxamide
CFAMM00313340 CHEMBL1083748 Bioactive N-(7-chloro-1-oxo-2H-isoquinolin-6-yl)-4-(3-methoxyphenyl)pyrrolidine-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543