CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5752
Family Name Epidermal growth factor receptor ligand AGN-PC-07C2E2 family
No. of Seeds 7 No. of Other Members 6
Family Centroid CFAMM00365952 Functional Category Bioactive
Superfamily Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibitor 6-phenyl-thieno[3,2-d]pyrimidin-4-ylamine Superfamily
Class Class 1151

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 6 64
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-ethy... 2 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 22
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Aurora kinase B and Aurora kinase A inhibitor AGN-PC-07ZBLC fa... 3 8
Vascular endothelial growth factor receptor 2 and Mast/stem ce... 10 27
Adenosine kinase inhibitor SureCN8183719 family 2 3
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 5 27
Histamine H4 receptor ligand 8-chloro-4-[(3R)-3-(methylamino)p... 3 10
Histamine H4 receptor ligand 8-bromo-4-(4-methylpiperazin-1-yl... 2 1
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(1,4-di... 3 3
Epidermal growth factor receptor ligand AGN-PC-076GWD family 2 0
Epidermal growth factor receptor and Vascular endothelial grow... 2 1
Epidermal growth factor receptor and Vascular endothelial grow... 7 0
Epidermal growth factor receptor and Vascular endothelial grow... 3 1
Vascular endothelial growth factor receptor 2 ligand Thienopyr... 2 2
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor AGN-P... 1 0
Vascular endothelial growth factor receptor 2 and Insulin rece... 2 0
Epidermal growth factor receptor ligand AGN-PC-075SGM family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00365960 CHEMBL151593 Bioactive AGN-PC-075SA6
CFAMM00365959 CHEMBL356850 Bioactive Benzothieno[3,2-d]pyrimidine deriv. 53
CFAMM00365952 CHEMBL539822 Bioactive AGN-PC-07C2E2
CFAMM00365958 CHEMBL358934 Bioactive AGN-PC-075SE6
CFAMM00365951 CHEMBL357570 Bioactive AGN-PC-075SED
CFAMM00365963 CHEMBL153573 Bioactive Benzothieno[3,2-d]pyrimidine deriv. 64
CFAMM00365956 CHEMBL152905 Bioactive Benzothieno[3,2-d]pyrimidine deriv. 61

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44466 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543