CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM576
Family Name Substance-K receptor ligand 5-chloro-N-[1-[[(2S)-5-[4-(oxan-4-ylmethyl)piperazin-1-yl]-1-phenylpentan-2-yl]carbamoyl]cyclopentyl]-1-benzofuran-2-carboxamide family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00313347 Functional Category Bioactive with Natural Product
Superfamily Cathepsin S and Cathepsin K Binder Superfamily
Class Class 2520

Cousin Family NamesSeedsMembers
Histone deacetylase Inhibitor Abexinostat Family 1 20
Sodium channel protein type 10 subunit alpha Ligand A-803467 F... 2 81
Histamine H3 receptor Ligand A-317920 Family 9 240
Protein kinase D Inhibitor CID755673 Family 1 1
Melatonin receptor type 1A and Melatonin receptor type 1B Liga... 33 98
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Sodium channel protein type 10 subunit alpha and Sodium channe... 2 13
Urotensin-2 receptor Ligand SB-436811 Family 6 71
Tryptase alpha/beta-1 and Tryptase delta inhibitor AGN-PC-074X... 5 6
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 11 4
Lethal(3)malignant brain tumor-like protein 1 and Lysine-speci... 1 6
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
Prostaglandin E2 receptor EP4 subtype ligand SureCN5653729 family 3 2
MAP kinase-activated protein kinase 2 inhibitor 5-(4-cyanophen... 3 8
Cathepsin S and Cathepsin K inhibitor arylaminoethyl amide, 7 ... 2 0
Translocator protein inhibitor N-[(2,5-dimethoxyphenyl)methyl]... 1 0
Histamine H3 receptor ligand SureCN5221194 family 1 8
Histamine H3 receptor ligand SureCN5218144 family 4 6
Histamine H3 receptor ligand SureCN5216152 family 1 0
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 4 13
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Histamine H1 receptor and Arachidonate 5-lipoxygenase ligand 1... 1 3
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 2 20
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 1
Gonadotropin-releasing hormone receptor ligand N-[[4-[(diamino... 6 4
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00AWDS ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00313348 CHEMBL1083847 Bioactive 5-methoxy-N-[1-[[(2S)-5-[4-(oxan-4-ylmethyl)piperazin-1-yl]-1-phenylpentan-2-yl]carbamoyl]cyclopentyl]-1-benzofuran-2-carboxamide
CFAMM00313347 CHEMBL1083846 Bioactive 5-chloro-N-[1-[[(2S)-5-[4-(oxan-4-ylmethyl)piperazin-1-yl]-1-phenylpentan-2-yl]carbamoyl]cyclopentyl]-1-benzofuran-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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