CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5760
Family Name Inosine-5'-monophosphate dehydrogenase inhibitor SureCN13182379 family
No. of Seeds 2 No. of Other Members 12
Family Centroid CFAMM00366114 Functional Category Bioactive with Natural Product
Superfamily Inosine-5'-monophosphate dehydrogenase and Adenosine kinase Binder Superfamily
Class Class 994

Cousin Family NamesSeedsMembers
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Benoxapr... 1 76
Substance-P receptor Ligand R 673 Family 2 127
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
Fatty-acid amide hydrolase 1 Inhibitor 1-(oxazolo[4,5-b]pyridi... 19 34
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxaz... 10 142
Prostacyclin receptor and Prostaglandin E2 receptor EP3 subtyp... 4 17
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Fatty-acid amide hydrolase 1 Inhibitor 3-(benzo[d]oxazol-2-yl)... 1 6
Peroxisome proliferator-activated receptor delta ligand SureCN... 8 19
Muscarinic acetylcholine receptor M3 ligand [(3R)-1-[3-(1,3-be... 3 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 21
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 4 15
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Thyroid hormone receptor beta ligand CHEMBL1397256 family 1 12
Thromboxane-A synthase and Thromboxane A2 receptor ligand Sure... 5 37
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
Fatty-acid amide hydrolase 1 inhibitor [(2S)-6-phenoxy-1,2,3,4... 3 6
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 19
Fatty-acid amide hydrolase 1 and Liver carboxylesterase 1 inhi... 2 2
Sphingosine 1-phosphate receptor 1 ligand 6-[2-[4-phenyl-3-(tr... 2 3
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 14 24
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 1 1
Peroxisome proliferator-activated receptor gamma and Peroxisom... 3 0
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 4jj ... 1 1
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 5a f... 2 1
Inosine-5'-monophosphate dehydrogenase inhibitor (2S)-2-(2,3-d... 1 1
Inosine-5'-monophosphate dehydrogenase inhibitor 2-(2,3-dichlo... 2 0
Inosine-5'-monophosphate dehydrogenase inhibitor (2S)-2-(2,3-d... 4 1
Inosine-5'-monophosphate dehydrogenase inhibitor (2S)-2-naphth... 1 0
Bifunctional epoxide hydrolase 2 inhibitor 8-(quinoline-5-carb... 1 0
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 5
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 11 3
Mitogen-activated protein kinase 14 inhibitor 4-[4-(4-fluoroph... 1 5
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-04UH7Y family 4 1
B2 bradykinin receptor ligand 1-N,3-N-dimethyl-4-[methyl-[2-[[... 4 1
Collagenase 3 inhibitor SureCN1316041 family 4 3
Metabotropic glutamate receptor 5 ligand SureCN504754 family 5 4
Diacylglycerol O-acyltransferase 1 inhibitor SureCN2789698 family 2 8
Fatty-acid amide hydrolase 1 inhibitor 2-[5-[5-(5-chloropyridi... 1 0
Metabotropic glutamate receptor 5 ligand 3-fluoro-5-(5-pyridin... 1 0
Fatty-acid amide hydrolase 1 inhibitor 7-phenyl-1-[5-[6-(2H-te... 2 0
Neuropeptide Y receptor type 1 ligand 1-(1,3-benzoxazol-5-yl)-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00366114 CHEMBL2348818 Bioactive SureCN13182379
CFAMM00366119 CHEMBL2348823 Bioactive (2S)-2-naphthalen-1-yloxy-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)propanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27619 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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