CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5797
Family Name 5-hydroxytryptamine receptor 6 ligand 8-chloro-2-(4-methoxy-3-piperazin-1-ylphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00366330 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 and Growth hormone secretagogue receptor type 1 Binder Superfamily
Class Class 2913

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 6 Ligand Sb 258585 Family 11 121
5-hydroxytryptamine receptor 6 Ligand SB-357134 Family 13 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 20 33
Pyruvate kinase PKLR and Pyruvate kinase PKM inhibitor AGN-PC-... 1 1
5-hydroxytryptamine receptor 6 ligand N-(3,5-dichlorophenyl)-4... 7 2
Alpha-2A adrenergic receptor and 5-hydroxytryptamine receptor ... 7 10
5-hydroxytryptamine receptor 6 ligand 1-(4-methoxy-3-piperazin... 6 3
5-hydroxytryptamine receptor 6 ligand 6-bromo-1-(4-methoxy-3-p... 2 0
5-hydroxytryptamine receptor 6 ligand AGN-PC-0BRZ7B family 9 2
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 10 1
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 5 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 1
Growth hormone secretagogue receptor type 1 ligand SureCN48020... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-met... 3 3
5-hydroxytryptamine receptor 6 ligand N-(3-bromo-2,5-dichlorop... 2 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 3 3
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 1


External ID

Functional Category

Molecule Name

CFAMM00366327 CHEMBL156130 Bioactive N-(4-chloro-2-methoxy-5-methylphenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
CFAMM00366326 CHEMBL151998 Bioactive 5,7-dichloro-1-(4-methoxy-3-piperazin-1-ylphenyl)sulfonyl-3,4-dihydro-2H-quinoline
CFAMM00366330 CHEMBL157173 Bioactive 8-chloro-2-(4-methoxy-3-piperazin-1-ylphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline
CFAMM00366329 CHEMBL157454 Bioactive 5,8-dichloro-2-(4-methoxy-3-piperazin-1-ylphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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