CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5852
Family Name Prelamin-A/C and Ferritin light chain inhibitor CHEMBL1524039 family
No. of Seeds 3 No. of Other Members 61
Family Centroid CFAMM00368324 Functional Category Bioactive with Human Metabolite & Natural Product
Superfamily Prelamin-A/C and Ferritin light chain inhibitor CHEMBL1524039 Superfamily
Class Class 4338

Cousin Family NamesSeedsMembers
Androgen receptor ligand Anabolic steroid Dromostanolone Family 9 408
Biliverdin reductase A and Solute carrier Family 23 member 2 i... 9 112
DNA polymerase catalytic subunit Inhibitor Aphidicolin Family 2 38
DNA topoisomerase 2-beta Inhibitor Lupeol Family 2 23
Sex hormone-binding globulin inhibitor (5S,8R,9S,10S,13S,14S,1... 1 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 3
Sex hormone-binding globulin inhibitor (1S,5S,8R,9S,10S,13S,14... 1 6
Androgen receptor ligand 10-[(5S,7R,8R,9S,10S,13S,14S,17S)-17-... 1 0
M-phase inducer phosphatase 1 inhibitor 2-[[(3S,5S,8R,9S,10S,1... 1 0
Prenol Lipids Metabolite gamma-Taraxastane-3,20-diol Family 1 11
Prenol Lipids Metabolite 3-(5,6,6-Trimethylbicyclo[2.2.1]hept-... 1 8
Prenol Lipids Metabolite (-)-Borneol Family 6 1
Prenol Lipids Metabolite (ent-16alpha)-16-Kauranol Family 1 0


External ID

Functional Category

Molecule Name

CFAMM00368391 CHEMBL335062 Bioactive Hombreol
CFAMM00368339 CHEMBL261643 Bioactive (3S,5S,7R,8R,9S,10S,13S,14S,17S)-7,10,13-trimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol
CFAMM00368319 CHEMBL430043 Bioactive (3S,5S,7R,8R,9S,10S,13S,14S,17S)-7,10,13,17-tetramethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,17-diol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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