Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database. Cousin Family Names Seeds Members Leutinizing-hormone-releasing hormone inhibitor peptide Leupro... 43 911 Parathyroid hormone/parathyroid hormone-related peptide recept... 55 256 Insulin receptor Ligand Insulin, Porcine Family 61 205 Insulin-degrading enzyme inhibitor cyclic polypeptide Bacitrac... 30 259 Renin Inhibitor Remikiren Family 100 126 Renin Inhibitor Enalkiren Family 56 44 Caspase-9 Inhibitor Z-lehd-fmk Family 1 0 Renin Inhibitor (h-261)boc-his-pro-phe-his-leu(oh)-val-ile-his... 33 41 Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-his-agly-ile-v... 3 2 Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54 Glycylpeptide N-tetradecanoyltransferase Inhibitor SC-58272 Fa... 2 11 Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67 Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60 Type-1 angiotensin II receptor Ligand [sar1,tdf3]angii Family 135 2 Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7 Pol polyprotein inhibitor AC1LAD48 family 19 5 Renin and Cathepsin D inhibitor tert-butyl N-[(2R)-1-[[3-[[(2R... 19 4 Pol polyprotein inhibitor Hydroxyethylene deriv. 12 family 13 10 Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 11 22 Pol polyprotein inhibitor AC1LA3L0 family 3 2 Lysosomal Pro-X carboxypeptidase inhibitor N-[(2S)-1-[(2S)-2-(... 1 0 Renin and Cathepsin D inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-... 2 2 Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 3 Renin inhibitor (3R)-4-[[(2S,5S)-1-cyclohexyl-3-hydroxy-6-meth... 3 4 Pol polyprotein inhibitor propan-2-yl N-[(2S)-1-[[(2S,3S,5R)-3... 6 2 C-C chemokine receptor type 5 ligand AC1MHRXO family 5 1 Renin inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3S,5S)-5-(... 2 0 Renin inhibitor tert-butyl N-[1-[[1-[[(2S,3S)-1-cyclohexyl-3-h... 1 0 Renin inhibitor (2S)-N-[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(3-im... 4 0 Renin inhibitor (4S)-5-cyclohexyl-2,2-difluoro-4-[[(2S)-3-(1H-... 1 0 Renin inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cycl... 3 0 Renin inhibitor (2S,4S,5S)-6-cyclohexyl-4-hydroxy-N-(3-imidazo... 1 0 Renin inhibitor tert-butyl N-[1-[[1-[[(3R,4S)-1-cyclohexyl-3,4... 2 2 Renin inhibitor (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohe... 6 0 Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 3 Renin inhibitor [(2S)-1-[[(2R)-1-[[(2S,3S)-1-cyclohexyl-3-hydr... 1 0 Melanocyte-stimulating hormone receptor and Melanocortin recep... 1 0 Growth hormone secretagogue receptor type 1 ligand CHEMBL52599... 1 0
CFAM Mol ID
External ID
Functional Category
Molecule Name
CFAMM00368520 CHEMBL2115235 Bioactive
propan-2-yl (2R,3R)-4-cyclohexyl-2-hydroxy-3-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2R)-4-morpholin-4-yl-2-(naphthalen-1-ylmethyl)-4-oxobutanoyl]amino]propanoyl]amino]butanoate CFAMM00368519 CHEMBL152610 Bioactive
[(2S)-1-[[1-[[(2S,3R,4R,5R,6R)-1-cyclohexyl-3,4,5,6,7-pentahydroxyheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl] N-methyl-N-[2-[methyl(morpholine-4-carbonyl)amino]ethyl]carbamate CFAMM00368522 CHEMBL348587 Bioactive
106868-52-4 CFAMM00368521 CHEMBL330074 Bioactive
propan-2-yl (3R)-2-hydroxy-3-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2R)-4-morpholin-4-yl-2-(naphthalen-1-ylmethyl)-4-oxobutanoyl]amino]propanoyl]amino]-5-methylhexanoate
CFAM Mol ID
External ID
Functional Category
Molecule Name
Statistics of CFAM Database
490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
How to cite our database
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering.
Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
Last update by
2014.08.29
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Chen Yuzong Deputy
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