CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5888
Family Name Gastrin/cholecystokinin type B receptor and Cholecystokinin receptor type A ligand [(5S,7R)-2-chloro-1-adamantyl] N-[(2R)-1-[[(2S)-1-hydroxy-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-2-methyl-1-oxopropan-2-yl]carbamate family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00174751 Functional Category Bioactive
Superfamily Bacterial outer membrane Inhibitor Daptomycin Superfamily
Class Class 647

Cousin Family NamesSeedsMembers
Alpha adrenergic receptor ligand ergot alkaloid Dihydroergota... 7 12
HIV protease Inhibitor Indinavir Family 36 211
HIV protease Inhibitor Saquinavir Family 64 428
Gastrin/cholecystokinin type B receptor ligand peptide Pentaga... 26 1171
Somatostatin receptor type 2 ligand octapeptide Octreotide Family 27 172
HIV-1 protease Inhibitor Atazanavir Family 16 58
Gastrin/cholecystokinin type B receptor ligand oligopeptide Ce... 35 209
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Bacterial outer membrane Inhibitor Daptomycin Family 6 50
Somatostatin receptor type 2 ligand octapeptide Lanreotide Family 93 156
ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
Substance-P receptor Ligand GSK424887 Family 8 184
Growth hormone receptor Ligand EP-51216 Family 34 390
CBP-501 family 7 8
Cholecystokinin receptor type A Ligand A-71378 Family 77 23
Gastrin/cholecystokinin type B receptor Ligand PD136450 Family 53 117
Lethal factor Inhibitor GM6001 Family 50 435
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Cathepsin B and Cathepsin K Inhibitor Z-arg-leu-val-agly-ile-v... 3 19
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Delta-type opioid receptor and Gastrin/cholecystokinin type B ... 19 0
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[n... 12 10
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Delta-type opioid receptor Ligand H-poa-ser-gly-phe-leu-thr-oh... 5 12
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Angiotensin-converting enzyme and Endothelin-converting enzyme... 2 10
Endothelin B receptor Ligand IRL-2500 Family 34 87
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 46 0
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
C-C chemokine receptor type 5 ligand AC1LAJEM family 4 14
Pol polyprotein inhibitor pyridin-2-ylmethyl N-[(2R)-1-[[(2S,3... 15 8
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... 6 2
Pol polyprotein inhibitor Hydroxyethylene deriv. 12 family 13 10
Pol polyprotein inhibitor N-[(2S)-1-[[(2S,3R,4S,5S)-3,4-dihydr... 2 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 17 28
Neutrophil collagenase and Stromelysin-3 inhibitor AC1MORIH fa... 7 9
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 0
Pol polyprotein inhibitor Carbamic acid, ((2-hydroxy-1,4-bis(p... 21 1
Prothrombin and Cationic trypsin inhibitor tert-butyl N-[(2R)-... 4 3
Prothrombin inhibitor (2S)-N-[(6-carbamimidoylpyridin-3-yl)met... 2 14
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 1 2
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 4 53
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 0
Growth hormone-releasing hormone receptor ligand ethyl (1S)-1'... 3 2
Somatostatin receptor type 2 ligand (2R,3S)-N-[(5-amino-1,3-di... 2 5
Somatostatin receptor type 4 ligand methyl 5-(diaminomethylide... 2 34
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Pol polyprotein inhibitor (2S,4S,5S)-5-acetamido-6-cyclohexyl-... 3 3
Interstitial collagenase and Matrilysin inhibitor (2S,3R)-N,2-... 3 1
Substance-P receptor ligand N-[(2S)-5-[3,5-bis(trifluoromethyl... 4 6
Renin and Potassium voltage-gated channel subfamily H member 2... 9 2
Muscarinic acetylcholine receptor M3 ligand [(3R)-1-[2-(1H-ind... 1 0
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 3 0
Pancreatic alpha-amylase and Gastrin/cholecystokinin type B re... 7 1
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 4
C-C chemokine receptor type 2 ligand SureCN5946889 family 2 6
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 4
Renin inhibitor tert-butyl N-[1-[[1-[[1-cyclohexyl-4,4-difluor... 5 0
Protein kinase C delta type and Protein kinase C beta type inh... 4 4
Endothelin B receptor and Endothelin-1 receptor ligand 2-[[(2R... 17 10
Neutrophil collagenase and Stromelysin-3 inhibitor [3-[[1-amin... 3 2
Growth factor receptor-bound protein 2 ligand 2-[4-[(2S)-3-[[1... 1 0
Gastrin/cholecystokinin type B receptor ligand (2R)-2-[[5-(8-a... 2 3
Substance-P receptor ligand (4R)-N-[(2R)-1-[benzyl(methyl)amin... 8 5
Bombesin receptor subtype-3 ligand SureCN13887096 family 3 1
Neprilysin and Endothelin-converting enzyme 1 inhibitor (2S)-2... 5 0
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... 2 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 2 2
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 3 1
Gastrin/cholecystokinin type B receptor ligand CHEMBL338525 fa... 1 10
KiSS-1 receptor ligand SureCN5132924 family 2 4
Angiotensin-converting enzyme inhibitor AC1L1IZN family 2 2
Prostaglandin D2 receptor 2 ligand AGN-PC-00QBAU family 1 24


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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