CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM589
Family Name Potassium voltage-gated channel subfamily H member 2 and Neuronal acetylcholine receptor subunit alpha-7 ligand (1S,4S)-2-[5-(1-benzofuran-5-yl)pyridin-2-yl]-5-methyl-2,5-diazabicyclo[2.2.1]heptane family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00313485 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and Adenosine receptor A1 Binder Superfamily
Class Class 1163

Cousin Family NamesSeedsMembers
Adenosine receptor A2a Ligand BIIB014 Family 26 92
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 3 44
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-(fur... 7 15
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Potassium voltage-gated channel subfamily H member 2 and Neuro... 1 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 20 28
Neuropeptide Y receptor type 5 ligand SureCN5771669 family 2 3
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-09ODY0 ... 2 5
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1938684 ... 5 6
Histamine H3 receptor ligand N-[[2-[2-[(2R)-2-methylpyrrolidin... 4 1
Melanin-concentrating hormone receptor 1 ligand 3-[6-[3-(dimet... 14 6
Melanin-concentrating hormone receptor 1 ligand 3-[6-[3-(dimet... 1 13
Adenosine kinase inhibitor AGN-PC-0757MS family 2 0
CGMP-dependent protein kinase inhibitor AGN-PC-075IHL family 2 8
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00313489 CHEMBL1085805 Bioactive (1S,4S)-2-[5-(1-benzofuran-5-yl)pyrimidin-2-yl]-5-methyl-2,5-diazabicyclo[2.2.1]heptane
CFAMM00313485 CHEMBL1085089 Bioactive (1S,4S)-2-[5-(1-benzofuran-5-yl)pyridin-2-yl]-5-methyl-2,5-diazabicyclo[2.2.1]heptane

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27620 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543