CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5891
Family Name D(4) dopamine receptor and D(2) dopamine receptor ligand N-(1-benzylpiperidin-4-yl)-6-chloro-5-(4-chlorophenyl)sulfanyl-2-methylpyrimidin-4-amine family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00368561 Functional Category Bioactive
Superfamily Aurora kinase A and Adenosine receptor A1 Binder Superfamily
Class Class 2142

Cousin Family NamesSeedsMembers
Amiloride-sensitive sodium channel subunit alpha Ligand Triamt... 8 98
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-amin... 4 11
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
Histamine H4 receptor Ligand A-943931 Family 14 11
Sodium-dependent serotonin transporter Inhibitor 6-chloro-2-pi... 5 35
Acetylcholinesterase Inhibitor N-benzyl-2-morpholinopyrimidin-... 6 16
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 6
Prostaglandin D2 receptor ligand N-[2-(2,4-dichlorophenyl)ethy... 1 0
Toll-like receptor 7 ligand 6-amino-2-(butylamino)-9-[[4-(dime... 5 4
Adenosine kinase inhibitor 4-[2-[5-(4-chlorophenyl)-6-piperazi... 3 1
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C9 inhib... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00368561 CHEMBL15270 Bioactive N-(1-benzylpiperidin-4-yl)-6-chloro-5-(4-chlorophenyl)sulfanyl-2-methylpyrimidin-4-amine
CFAMM00368562 CHEMBL33022 Bioactive UK 177

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26825 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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