CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5917
Family Name Inosine-5'-monophosphate dehydrogenase 2 inhibitor 7-methoxy-2-(4-methyl-3-morpholin-4-ylphenyl)-6-(1,3-oxazol-5-yl)-1H-quinolin-4-one family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00368686 Functional Category Bioactive
Superfamily Vascular endothelial growth factor receptor 2 Binder Superfamily
Class Class 656

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor and Receptor tyrosine-protein... 3 140
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
Vascular endothelial growth factor receptor 2 ligand 7-(6-acet... 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(2,3-... 2 0
Peroxisome proliferator-activated receptor delta and Peroxisom... 3 17
Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 4
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 3
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Mitogen-activated protein kinase 14 inhibitor SureCN4508019 fa... 1 0
Inosine-5'-monophosphate dehydrogenase 2 inhibitor 7-methoxy-6... 7 0


External ID

Functional Category

Molecule Name

CFAMM00368684 CHEMBL356881 Bioactive 7-methoxy-2-[4-methyl-3-(oxolan-2-ylmethoxy)phenyl]-6-(1,3-oxazol-5-yl)-1H-quinolin-4-one
CFAMM00368683 CHEMBL153481 Bioactive 7-methoxy-2-[4-methyl-3-(2-morpholin-4-ylethoxy)phenyl]-6-(1,3-oxazol-5-yl)-1H-quinolin-4-one
CFAMM00368682 CHEMBL422508 Bioactive SureCN5012537
CFAMM00368687 CHEMBL153118 Bioactive SureCN6484200
CFAMM00368686 CHEMBL153794 Bioactive 7-methoxy-2-(4-methyl-3-morpholin-4-ylphenyl)-6-(1,3-oxazol-5-yl)-1H-quinolin-4-one
CFAMM00368685 CHEMBL152910 Bioactive 2-(4-bromophenyl)-7-methoxy-6-(1,3-oxazol-5-yl)-1H-quinolin-4-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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