CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM596
Family Name Rho-associated protein kinase 2 inhibitor N-(7-chloro-1-oxo-2H-isoquinolin-6-yl)-4-pyridin-3-ylpyrrolidine-3-carboxamide family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00313575 Functional Category Bioactive
Superfamily ABC294640 Superfamily
Class Class 913

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Neuromedin-K receptor Ligand SB222200 Family 17 235
D(3) dopamine receptor Ligand SB-277011 Family 13 178
XL-888 family 16 85
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Transient receptor potential cation channel subfamily V member... 6 23
Peroxisome proliferator-activated receptor gamma Ligand 2-chlo... 5 19
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
RAC-alpha serine/threonine-protein kinase and Cyclin-dependent... 3 7
Reverse transcriptase/RNaseH inhibitor AGN-PC-0755HU family 1 0
Coagulation factor X inhibitor AGN-PC-078Y0T family 11 0
Macrophage colony-stimulating factor 1 receptor ligand AGN-PC-... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00313575 CHEMBL1084104 Bioactive N-(7-chloro-1-oxo-2H-isoquinolin-6-yl)-4-pyridin-3-ylpyrrolidine-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24517 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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