CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM597
Family Name Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3-methoxy-4-naphthalen-1-ylphenyl)-[(1R,5S)-3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl]methanone family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00183991 Functional Category Bioactive
Superfamily Vasopressin V2 receptor and Vasopressin V1a receptor Binder Superfamily 3
Class Class 893

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
D(2) dopamine receptor Ligand Remoxipride Family 12 84
Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
Microsomal triglyceride transfer protein large subunit Inhibit... 3 103
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
5-hydroxytryptamine receptor 1A Ligand Robalzotan Family 9 41
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Histamine H3 receptor Ligand A-317920 Family 9 240
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 8 66
Histamine H3 receptor Ligand A-349821 Family 49 228
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 2 10
Caspase-3 Inhibitor 2-(4-methoxy-benzyl)isoquinoline-1,3,4-tri... 2 2
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Acetylcholinesterase and Cholinesterase Inhibitor Caproctamine... 7 17
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 33
Melatonin receptor type 1A and Melatonin receptor type 1B Liga... 33 98
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 14
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
D(2) dopamine receptor Ligand Epidepride Family 31 66
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 95 46
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Vasopressin V1a receptor and Vasopressin V2 receptor ligand [4... 4 7
Vasopressin V1a receptor and Vasopressin V2 receptor ligand [4... 2 3
Vasopressin V1a receptor and Vasopressin V2 receptor ligand N-... 1 2
Disintegrin and metalloproteinase domain-containing protein 17... 28 10
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
D(4) dopamine receptor and D(3) dopamine receptor ligand N-[(3... 2 11
Leukotriene B4 receptor 1 ligand AGN-PC-00GEAR family 2 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 1
Substance-P receptor ligand AGN-PC-075NP5 family 4 8
Mu-type opioid receptor ligand 3-[(3R,4R)-1-[(2,4-dimethoxyphe... 2 4
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 2
Prelamin-A/C and Retinal dehydrogenase 1 inhibitor CHEMBL15810... 1 1
Pol polyprotein inhibitor CHEMBL305466 family 4 7
Histamine H1 receptor and Histamine H3 receptor ligand 4-[(4-m... 3 6
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 3
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 7 18
Growth hormone secretagogue receptor type 1 ligand 2-[(2S)-1-[... 2 0
Nociceptin receptor and Kappa-type opioid receptor ligand AGN-... 1 3
Histamine H3 receptor ligand 4-[[2-[2-[(2R)-2-methylpyrrolidin... 1 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 6 2
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 15 4
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 3
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 2 4
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 15
Sigma non-opioid intracellular receptor 1 and D(3) dopamine re... 26 8
Melanin-concentrating hormone receptor 1 ligand N-methyl-N-[(3... 2 2
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-04X9O... 2 1
Muscarinic acetylcholine receptor M3 ligand N-[[3-[3-[(3-methy... 5 2
C-C chemokine receptor type 3 and Probable C-C chemokine recep... 5 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00313576 CHEMBL1085301 Bioactive [4-(1-benzofuran-3-yl)-3-methoxyphenyl]-[(1R,5S)-3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl]methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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