CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM5999
Family Name Survival motor neuron protein and Microtubule-associated protein tau inhibitor CHEMBL1536054 family
No. of Seeds 1 No. of Other Members 20
Family Centroid CFAMM00369217 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and Beta-lactamase Binder Superfamily 2
Class Class 3094

Cousin Family NamesSeedsMembers
Leukotriene A-4 hydrolase Inhibitor 4-(2-amino-1,3-thiazol-4-y... 3 13
Adenosine receptor A1 and Adenosine receptor A2a Ligand LUF-54... 2 19
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 1 20
Histone deacetylase 1 and Histone deacetylase 2 inhibitor N-hy... 2 3
Aurora kinase A inhibitor AGN-PC-00BCUF family 16 43
Nuclear receptor ROR-gamma and 15-hydroxyprostaglandin dehydro... 1 3
Receptor-type tyrosine-protein kinase FLT3 ligand 2-(6,7-dimet... 3 2
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 5 7
Neuropeptides B/W receptor type 1 ligand [4-(1H-benzimidazol-2... 6 4
Cholinesterase and Acetylcholinesterase inhibitor 3-[ethyl-[3-... 2 3
Sphingosine kinase 1 and Sphingosine kinase 2 inhibitor (2R,4S... 9 8
Deoxycytidine kinase inhibitor 2-[5-[4-[(4,6-diaminopyrimidin-... 14 11
Neuropeptide Y receptor type 5 ligand 1-[4-[[(9-methyl-4,5-dih... 5 6
Adenosine receptor A1 ligand 7-methoxy-4,5-dihydrobenzo[e][1,3... 2 2
Vascular endothelial growth factor receptor 2 ligand aminothia... 1 1
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 2
Urokinase-type plasminogen activator inhibitor AGN-PC-01XMBP f... 3 7
A disintegrin and metalloproteinase with thrombospondin motifs... 2 4
Histone deacetylase 1 inhibitor (2S)-2-[[2-(5-methoxy-2-methyl... 2 2
DNA-(apurinic or apyrimidinic site) lyase and DNA polymerase b... 1 0


External ID

Functional Category

Molecule Name

CFAMM00369201 CHEMBL324429 Bioactive N'-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-N-methyl-2-oxononanediamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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