CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Transient receptor potential cation channel subfamily V member 1 ligand 1-[[2-(2,2-dimethylpropoxy)-6-(trifluoromethyl)pyridin-3-yl]methyl]-3-(1H-indazol-4-yl)urea family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00313622 Functional Category Bioactive
Superfamily Transient receptor potential cation channel subfamily V member 1 and Rho-associated protein kinase 2 Binder Superfamily
Class Class 1301

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor and Receptor tyrosine-protein... 8 31
D(2) dopamine receptor and D(3) dopamine receptor Ligand Benzy... 2 9
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 50 36
Transient receptor potential cation channel subfamily V member... 7 17
Vascular endothelial growth factor receptor 2 ligand AGN-PC-09... 5 11
Rho-associated protein kinase 2 inhibitor 1-ethyl-1-[(3-methox... 15 8
P2Y purinoceptor 1 inhibitor 1-(4-tert-butylphenyl)-3-[2-(2-pr... 4 14
Cell division cycle 7-related protein kinase inhibitor SureCN4... 1 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 25 0


External ID

Functional Category

Molecule Name

CFAMM00313622 CHEMBL1084293 Bioactive 1-[[2-(2,2-dimethylpropoxy)-6-(trifluoromethyl)pyridin-3-yl]methyl]-3-(1H-indazol-4-yl)urea
CFAMM00313621 CHEMBL1085786 Bioactive 1-(1H-indazol-4-yl)-3-[[2-phenoxy-6-(trifluoromethyl)pyridin-3-yl]methyl]urea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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