CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6034
Family Name Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ligand N-[(2R,11bS)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl]-N,4-dimethylbenzenesulfonamide family
No. of Seeds 3 No. of Other Members 34
Family Centroid CFAMM00369498 Functional Category Bioactive
Superfamily Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor Binder Superfamily 5
Class Class 4371

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
5-hydroxytryptamine receptor 7 and D(2) dopamine receptor Liga... 3 29
5-hydroxytryptamine receptor 5A and 5-hydroxytryptamine recept... 12 20
Potassium voltage-gated channel subfamily H member 2 Ligand 4-... 4 26
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 4 4
Alpha-2A adrenergic receptor Ligand SK&F-29661 Family 3 42
Melanin-concentrating hormone receptor 1 Ligand N,n-bis(tosylm... 2 1
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Acetylcholinesterase Inhibitor 1-benzene Sulfonyl-cis-2,6-dime... 1 4
Oxytocin receptor and Vasopressin V1a receptor Ligand 1'-tosyl... 1 7
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 17 9
Squalene synthase Inhibitor Zwitterionic Sulfobetaine Derivati... 2 20
C-C chemokine receptor type 5 ligand AC1LAJBJ family 2 19
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 7
Sodium-dependent serotonin transporter and Sodium-dependent no... 12 0
Survival motor neuron protein and Inositol monophosphatase 1 i... 1 4
C-C chemokine receptor type 5 ligand methyl N-[1-[(3S)-4-[benz... 3 18
Histamine H3 receptor ligand 2-[4-[4-[2-[(2R)-2-methylpyrrolid... 4 11
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 6 4
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 14 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 10
Growth hormone secretagogue receptor type 1 ligand SureCN47963... 3 3
Sigma non-opioid intracellular receptor 1 ligand 1-benzyl-4-[(... 3 2
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 7
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 4 0
C-C chemokine receptor type 5 ligand AC1L9YN4 family 2 33
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 2 2
Neuropeptide Y receptor type 5 and Neuropeptide Y receptor typ... 1 5
Histamine H3 receptor and Potassium voltage-gated channel subf... 5 0
Histamine H3 receptor ligand N,N-diethyl-4-[4-[2-[(2R)-2-methy... 4 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 0
C-C chemokine receptor type 3 ligand 4-(benzenesulfonyl)-N-[(1... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00369494 CHEMBL277737 Bioactive N-[(2R,11bS)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl]-N-methylbenzenesulfonamide
CFAMM00369498 CHEMBL30829 Bioactive N-[(2R,11bS)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl]-N,4-dimethylbenzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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