CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6045
Family Name Type-2 angiotensin II receptor ligand SureCN244657 family
No. of Seeds 7 No. of Other Members 11
Family Centroid CFAMM00369544 Functional Category Bioactive
Superfamily Prelamin-A/C and Cellular tumor antigen p53 Binder Superfamily 4
Class Class 92

Cousin Family NamesSeedsMembers
Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Multidrug resistance protein Inhibitor Benzquinamide Family 1 41
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Endothelin-1 receptor Ligand Atrasentan Family 127 336
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Histamine H3 receptor Ligand A-349821 Family 49 228
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 4
D(2) dopamine receptor Ligand (s)-secoantioquine Family 1 10
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor 2-[3-[(1R... 9 46
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Endothelin-1 receptor and Endothelin B receptor ligand (2R,3R,... 5 4
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL14038... 1 9
Prelamin-A/C and Retinal dehydrogenase 1 inhibitor CHEMBL15810... 1 1
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 12 0
Growth hormone secretagogue receptor type 1 ligand tert-butyl ... 5 4
Growth hormone secretagogue receptor type 1 ligand 2-(2-acetyl... 2 0
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 28
Prostaglandin D2 receptor 2 and Chemoattractant receptor-homol... 1 1
Kappa-type opioid receptor and Delta-type opioid receptor liga... 1 3
Cannabinoid receptor 1 ligand AGN-PC-03RV6L family 10 3
Free fatty acid receptor 1 ligand (3R,4R)-3-[4-(3,4-dimethylph... 4 4
Neuropeptide Y receptor type 1 and Sodium-dependent serotonin ... 2 7
Dipeptidyl peptidase 4 inhibitor SureCN664019 family 4 5
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor SureCN101... 2 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00369544 CHEMBL155836 Bioactive SureCN244657
CFAMM00369529 CHEMBL154057 Bioactive SureCN3517217
CFAMM00369542 CHEMBL156129 Bioactive AGN-PC-03OSB8
CFAMM00369535 CHEMBL155728 Bioactive SureCN3514145
CFAMM00369540 CHEMBL34124 Bioactive PD-126055
CFAMM00369546 CHEMBL348363 Bioactive AGN-PC-075UFM
CFAMM00369545 CHEMBL156100 Bioactive AGN-PC-03OSBM

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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