CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM608
Family Name Glucocorticoid receptor ligand N-[(3S)-3-[1-(4-fluorophenyl)indazol-5-yl]-2-methyl-3-phenylpropyl]ethanesulfonamide family
No. of Seeds 11 No. of Other Members 24
Family Centroid CFAMM00313707 Functional Category Bioactive
Superfamily Glucocorticoid receptor and Coagulation factor X Binder Superfamily
Class Class 2728

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 6 Ligand 4-(4,6-dinitro-1h-indol-... 4 19
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
Glucocorticoid receptor and Oxysterols receptor LXR-alpha Liga... 4 13
Protein kinase C theta type and Protein kinase C delta type in... 7 17
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 10 1
Glucocorticoid receptor ligand 2,4,6-trimethyl-N-[(2S)-1-[[6-m... 16 1
Progesterone receptor and Mineralocorticoid receptor ligand AG... 6 1
5-hydroxytryptamine receptor 2A ligand SureCN5215979 family 2 10
Androgen receptor ligand 2-chloro-4-[4-[(4-fluorophenyl)methyl... 2 11
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 1
Glucocorticoid receptor ligand 3,3,3-trifluoro-N-[(3S)-3-[1-(4... 10 4
Glucocorticoid receptor ligand (4aR)-1-(4-fluorophenyl)-4a-(me... 18 2
Glucocorticoid receptor ligand 1-[(4aS)-6-(4-tert-butylphenyl)... 27 3
Glucocorticoid receptor ligand 4-[[(4aS)-6-(4-tert-butylphenyl... 4 0
Glucocorticoid receptor ligand 6-benzyl-1-(4-fluorophenyl)-4a-... 2 0
Progesterone receptor ligand AGN-PC-074LWG family 1 1
Glucocorticoid receptor ligand N-ethyl-4-fluoro-N-[3,3,3-trifl... 2 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00313689 CHEMBL2426115 Bioactive N-[(3S)-3-[1-(4-fluorophenyl)indazol-5-yl]-2,2-dimethyl-3-phenylpropyl]ethanesulfonamide
CFAMM00313708 CHEMBL2426120 Bioactive N-[(3S)-3-[1-(4-fluorophenyl)indazol-5-yl]-2-methyl-3-phenylpropyl]methanesulfonamide
CFAMM00313688 CHEMBL2426114 Bioactive N-[(3S)-3-[1-(4-fluorophenyl)indazol-5-yl]-2,2-dimethyl-3-phenylpropyl]methanesulfonamide
CFAMM00313681 CHEMBL1085625 Bioactive N-[4-[1-(4-fluorophenyl)indazol-5-yl]-3-(trifluoromethyl)phenyl]ethanesulfonamide
CFAMM00313707 CHEMBL2426121 Bioactive N-[(3S)-3-[1-(4-fluorophenyl)indazol-5-yl]-2-methyl-3-phenylpropyl]ethanesulfonamide
CFAMM00313687 CHEMBL2426117 Bioactive N-[(3S)-3-[1-(4-fluorophenyl)indazol-5-yl]-2,2-dimethyl-3-phenylpropyl]cyclopropanesulfonamide
CFAMM00313693 CHEMBL2426119 Bioactive 2,2,2-trifluoro-N-[(3S)-3-[1-(4-fluorophenyl)indazol-5-yl]-2-methyl-3-phenylpropyl]ethanesulfonamide
CFAMM00313686 CHEMBL2426116 Bioactive N-[(3S)-3-[1-(4-fluorophenyl)indazol-5-yl]-2,2-dimethyl-3-phenylpropyl]propane-1-sulfonamide
CFAMM00313712 CHEMBL1086484 Bioactive N-[4-[1-(4-fluorophenyl)indazol-5-yl]-3-(trifluoromethyl)phenyl]-1-phenylmethanesulfonamide
CFAMM00313692 CHEMBL2426118 Bioactive 2,2,2-trifluoro-N-[(3S)-3-[1-(4-fluorophenyl)indazol-5-yl]-2,2-dimethyl-3-phenylpropyl]ethanesulfonamide
CFAMM00313685 CHEMBL1084360 Bioactive N-[4-[1-(4-fluorophenyl)indazol-5-yl]-3-(trifluoromethyl)phenyl]methanesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27514 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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