CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6092
Family Name Prelamin-A/C and Ras-related protein Rab-9A inhibitor CHEMBL1545412 family
No. of Seeds 1 No. of Other Members 7
Family Centroid CFAMM00369820 Functional Category Bioactive
Superfamily Prelamin-A/C and Ras-related protein Rab-9A inhibitor CHEMBL1545412 Superfamily
Class Class 2042

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Palonosetron Family 12 403
Amine oxidase [flavin-containing] A Inhibitor Moclobemide Family 5 255
Glutathione S-transferase Inhibitor Praziquantel Family 5 167
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
Neuromedin-K receptor Ligand Osanetant Family 38 192
Substance-K receptor and Substance-P receptor Ligand DNK-333 F... 15 95
Bavisant family 9 65
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Poly(ADP-ribose) glycohydrolase Inhibitor N-bis-(3-phenyl-prop... 3 7
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 10 52
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 2 23
Serine/threonine-protein kinase Chk1 Inhibitor 6-(3-aminopropy... 2 7
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
5-hydroxytryptamine receptor 2A Ligand N-(1-(3-bromobenzyl)pip... 6 10
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 3 18
C-C chemokine receptor type 5 ligand AC1NUIO8 family 12 11
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 2
Vasopressin V1a receptor and Vasopressin V2 receptor ligand [2... 2 4
C-C chemokine receptor type 5 ligand AC1L9USC family 3 2
Kappa-type opioid receptor ligand 6-[2-oxo-2-[(2S)-2-(pyrrolid... 6 4
Sigma non-opioid intracellular receptor 1 ligand N-Phprop-clph... 1 12
Substance-P receptor ligand AGN-PC-075NUD family 4 1
Acetylcholinesterase inhibitor 5-benzoyl-2-[2-(1-benzylpiperid... 2 3
Pyruvate kinase PKM and Huntingtin inhibitor CHEMBL1455935 family 1 3
Prothrombin inhibitor AGN-PC-09QJ23 family 2 5
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[[2-(2,4-dic... 4 9
Melanin-concentrating hormone receptor 1 ligand 1-(3-acetyl-1,... 8 4
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 2 0
Lysosomal Pro-X carboxypeptidase inhibitor (2S,3S)-2-[(2-amino... 3 3
Oxytocin receptor and Vasopressin V2 receptor ligand (2R)-2-(2... 4 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 9 0
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (3R... 6 1
Sodium-dependent serotonin transporter and Sodium-dependent do... 6 3
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 8 4
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 4
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-2-chloro-5-... 3 1
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Histamine H3 receptor ligand AGN-PC-01WA6E family 10 1
Sodium-dependent dopamine transporter and Transporter inhibito... 6 0
Melanin-concentrating hormone receptor 1 and Potassium voltage... 1 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 0
Aldose reductase inhibitor SureCN8804611 family 2 0
Substance-P receptor ligand 1-benzyl-3-[bis(4-chlorophenyl)met... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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