CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6114
Family Name Calcitonin gene-related peptide type 1 receptor and Dual specificity mitogen-activated protein kinase kinase 2 ligand AGN-PC-07CQ34 family
No. of Seeds 8 No. of Other Members 4
Family Centroid CFAMM00369967 Functional Category Bioactive
Superfamily Aldose reductase and Calcitonin gene-related peptide type 1 receptor Binder Superfamily
Class Class 1613

Cousin Family NamesSeedsMembers
Alpha adrenergic receptor Ligand Droperidol Family 20 244
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Motilin receptor Ligand GSK962040 Family 30 457
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Cannabinoid receptor 1 Ligand 1,3,5-triphenylimidazolidine-2,4... 2 17
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 5 2
B2 bradykinin receptor ligand AGN-PC-074WA4 family 2 3
Calcitonin gene-related peptide type 1 receptor ligand N,N-dim... 12 32
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 5 14
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 4 6
Disintegrin and metalloproteinase domain-containing protein 17... 1 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 15 12
Hypoxia-inducible factor 1-alpha and Ubiquitin carboxyl-termin... 1 1
5-hydroxytryptamine receptor 1A ligand SureCN4244417 family 10 1
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 2 0
Calcitonin gene-related peptide type 1 receptor and Cytochrome... 2 17
Nociceptin receptor and Mu-type opioid receptor ligand N,N-dim... 5 4
Nociceptin receptor ligand 2-[3-[1-[(1R)-1,2-dihydroacenaphthy... 2 0
5-hydroxytryptamine receptor 7 ligand 2-[4-[4-(2-oxo-1,3,4,5-t... 1 0
Growth hormone secretagogue receptor type 1 ligand SureCN77944... 1 2
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 11 4
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 5
Capsid scaffolding protein inhibitor AC1LAC5B family 1 39
Calcitonin gene-related peptide type 1 receptor and Dual speci... 4 0
C5a anaphylatoxin chemotactic receptor 1 ligand SureCN12047568... 1 1
Aldose reductase inhibitor (4R)-6-fluoro-3-methylspiro[1H-quin... 4 16


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00369959 CHEMBL568921 Bioactive AGN-PC-07CQ3F
CFAMM00369965 CHEMBL569340 Bioactive N-[(3,5-difluorophenyl)methyl]-2,2-dimethyl-N-[2-[[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]amino]-2-oxoethyl]propanamide
CFAMM00369964 CHEMBL1547135 Bioactive T5652389
CFAMM00369961 CHEMBL570474 Bioactive N-[(1R)-1-(3,5-difluorophenyl)ethyl]-2,2-dimethyl-N-[2-[[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]amino]-2-oxoethyl]propanamide
CFAMM00369967 CHEMBL570488 Bioactive AGN-PC-07CQ34
CFAMM00369960 CHEMBL571580 Bioactive AGN-PC-07CQ2X

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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