CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6115
Family Name Prelamin-A/C inhibitor CHEMBL1547148 family
No. of Seeds 1 No. of Other Members 8
Family Centroid CFAMM00369986 Functional Category Bioactive
Superfamily Histone deacetylase 1 and Cellular tumor antigen p53 Binder Superfamily
Class Class 1000

Cousin Family NamesSeedsMembers
5-alpha reductase inhibitor azasteroid derivative Dutasteride ... 36 124
Serine/threonine-protein kinase Chk1 Inhibitor AZD7762 Family 26 90
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
Pan-DAC Inhibitor AR-42 Family 21 153
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Urokinase-type plasminogen activator Inhibitor 6-(n-phenylcarb... 2 11
Integrin alpha-2 and Integrin beta-3 Inhibitor 3-(3-(carbamoyl... 7 13
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 12 16
Histone deacetylase 1 and Potassium voltage-gated channel subf... 4 36
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 7 1
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 10 0
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 6 5
Coagulation factor X inhibitor benzothiophene compound, 4 family 9 10
Thyroid hormone receptor beta and Cellular tumor antigen p53 l... 1 4
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 4 19
Vasopressin V2 receptor and Vasopressin V1a receptor ligand 2-... 6 9
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075BLN ... 2 1
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 0
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-4-m... 1 0
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
Mitogen-activated protein kinase 14 inhibitor N-[3-[(11-oxo-5,... 2 0
Coagulation factor X and Prothrombin inhibitor SureCN6592460 f... 14 1
Coagulation factor X and Prothrombin inhibitor SureCN14502287 ... 16 5
Histone deacetylase 1 inhibitor SureCN3642893 family 10 23
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 10 0
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 3 5
Histone deacetylase 1 inhibitor Benzo[b]thiophene-2-carboxamid... 1 8
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 7 5
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 3
Vasopressin V2 receptor and Vasopressin V1a receptor ligand 2-... 4 0
Vascular endothelial growth factor receptor 2 ligand isoindoli... 1 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 1 0
Serine/threonine-protein kinase 33 inhibitor N-[5-fluoro-2-(3-... 1 3
Cyclin-dependent kinase 4 inhibitor SureCN3569974 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00369979 CHEMBL476542 Bioactive SureCN4812425

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27266 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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