CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6154
Family Name Kappa-type opioid receptor and Delta-type opioid receptor ligand 3-(5-fluoro-2-methoxyphenyl)-1-[2-(3-hydroxypyrrolidin-1-yl)-1-phenylethyl]pyridin-2-one family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00232119 Functional Category Bioactive
Superfamily Kappa-type opioid receptor and Lethal factor Binder Superfamily
Class Class 893

Cousin Family NamesSeedsMembers
Glucan synthesis regulatory protein Inhibitor Anidulafungin Fa... 2 5
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
Elagolix family 43 98
5-hydroxytryptamine receptor Ligand Bay X3702 Family 3 12
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 2 10
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Neutrophil elastase inhibitor (2S)-N-[(3S)-6-benzamido-5,5-dif... 6 10
Histamine H3 receptor ligand 1-(4-pentan-3-ylpiperazin-1-yl)-2... 1 1
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 2 13
Histamine H1 receptor and Histamine H3 receptor ligand 4-[(4-m... 3 6
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 6 3
Histamine H3 receptor ligand 1-methyl-5-[4-[3-[(2R)-2-methylpy... 5 5
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 7 10
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 4 0
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand N-[(... 1 0
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 4 3
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 3 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0
Kappa-type opioid receptor ligand N-[(1S)-2-[(3S)-3-hydroxypyr... 2 0
Renin inhibitor N-[(2S,3S,5R)-2-amino-6-(butylamino)-3-hydroxy... 5 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00370182 CHEMBL15498 Bioactive 1-[2-(3-hydroxypyrrolidin-1-yl)-1-phenylethyl]-3-[4-(trifluoromethoxy)phenyl]pyridin-2-one
CFAMM00370180 CHEMBL417260 Bioactive 3-(2,6-dimethoxyphenyl)-1-[2-(3-hydroxypyrrolidin-1-yl)-1-phenylethyl]pyridin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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