CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6158
Family Name C-C chemokine receptor type 2 and C-C chemokine receptor type 5 ligand N-(3,4-dichlorophenyl)-4-[(2R)-4-propan-2-ylpiperazine-2-carbonyl]piperazine-1-carboxamide family
No. of Seeds 2 No. of Other Members 8
Family Centroid CFAMM00270121 Functional Category Bioactive with Natural Product
Superfamily Beta-lactamase and Aminopeptidase N Binder Superfamily
Class Class 221

Cousin Family NamesSeedsMembers
Dopamine receptor Ligand Domperidone Family 2 21
C-C chemokine receptor type 3 Ligand Bertilimumab?? Family 3 9
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
Cannabinoid receptor 1 Ligand 1-(bis(4-chlorophenyl)methyl)-3-... 4 44
Histamine H3 receptor Ligand VUF-10214 Family 3 7
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 2 1
DNA topoisomerase Inhibitor 6-(3-iodo-phenylamino)-1h-pyrimidi... 2 5
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 4 18
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZBI0 family 2 16
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C8 inhib... 6 5
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 5 2
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 6 12
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 8 24
Survival motor neuron protein and 15-hydroxyprostaglandin dehy... 1 4
Substance-P receptor ligand (2S,4S)-2-N-[3-(diethylamino)propy... 2 7
D(3) dopamine receptor and D(2) dopamine receptor ligand 3-[4-... 4 23
Melanin-concentrating hormone receptor 1 ligand 1-[[4-[4-(3-cy... 14 23
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 5 2
D(3) dopamine receptor and D(2) dopamine receptor ligand RGH-1... 8 0
Melanin-concentrating hormone receptor 1 ligand SureCN14265866... 11 2
Renin inhibitor (E)-but-2-enedioic acid;(3S,5R)-5-[4-(2-chloro... 14 5
Substance-P receptor and Mu-type opioid receptor ligand ethyl ... 1 0
Histamine H3 receptor and Histamine receptor H3 ligand N-[4-[3... 5 1
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 3
Kappa-type opioid receptor ligand AGN-PC-077Q4Y family 5 9
Neuropeptide Y receptor type 5 ligand 3-[1-(3,5-difluorophenyl... 4 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 1
Type-2 angiotensin II receptor and Substance-P receptor ligand... 8 10
5-hydroxytryptamine receptor 2C ligand SureCN5872545 family 3 0
5-hydroxytryptamine receptor 2C ligand AGN-PC-00KC8G family 1 3
Melanin-concentrating hormone receptor 1 ligand SureCN13451707... 3 1
Neuropeptide Y receptor type 5 ligand 3-[1-(3,5-dichlorophenyl... 1 0
Neuropeptide Y receptor type 5 ligand SureCN6214451 family 3 1
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0
Type-2 angiotensin II receptor and Type-1 angiotensin II recep... 1 0
Type-2 angiotensin II receptor ligand SureCN3515537 family 1 0
Metabotropic glutamate receptor 5 and Beta-lactamase ligand 2-... 3 1
Gastrin/cholecystokinin type B receptor ligand 2-[5-cyclohexyl... 2 1
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 7 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00370198 CHEMBL346485 Bioactive SureCN7389067

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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