CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6159
Family Name Transient receptor potential cation channel subfamily V member 1 and Transient receptor potential cation channel subfamily V member 4 ligand AGN-PC-075U6X family
No. of Seeds 14 No. of Other Members 7
Family Centroid CFAMM00370209 Functional Category Bioactive
Superfamily Transient receptor potential cation channel subfamily V member 4 and Transient receptor potential cation channel subfamily V member 1 Binder Superfamily
Class Class 62

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
D(3) dopamine receptor Ligand U-99194A Family 7 33
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Arachidonate 5-lipoxygenase Inhibitor Bw A360C Family 12 8
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
Peptide deformylase, mitochondrial Inhibitor Tylophorinidine F... 7 1
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Tubulin beta chain Inhibitor Colchinol Family 3 109
D(2) dopamine receptor and D(1A) dopamine receptor Ligand 3-ch... 2 0
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 7 0
D(1A) dopamine receptor and D(3) dopamine receptor ligand N,N-... 3 1
Transient receptor potential cation channel subfamily V member... 1 0
7-dehydrocholesterol reductase inhibitor 2-[2-(4-chlorophenyl)... 2 3
Transient receptor potential cation channel subfamily V member... 4 40
Putative Bioactive 5-hexyl-2-[4-[(4-methylpiperazin-1-yl)methy... 2 0


External ID

Functional Category

Molecule Name

CFAMM00370219 CHEMBL415543 Bioactive 1-[3-(4-hydroxy-3-methoxyphenyl)propyl]-1,3-bis(2-phenylethyl)thiourea
CFAMM00370212 CHEMBL434295 Bioactive 1-[3-(4-hydroxy-3-methoxyphenyl)propyl]-3-(2-phenylethyl)-1-propan-2-ylthiourea
CFAMM00370205 CHEMBL157917 Bioactive AGN-PC-075UDN
CFAMM00370204 CHEMBL155730 Bioactive 1-benzyl-1-[3-(4-hydroxy-3-methoxyphenyl)propyl]-3-(2-phenylethyl)thiourea
CFAMM00370210 CHEMBL156693 Bioactive AGN-PC-075U8B
CFAMM00370223 CHEMBL422702 Bioactive AGN-PC-075U9F
CFAMM00370216 CHEMBL157962 Bioactive AGN-PC-075U9E
CFAMM00370209 CHEMBL158189 Bioactive AGN-PC-075U6X
CFAMM00370222 CHEMBL156041 Bioactive AGN-PC-075U9D
CFAMM00370215 CHEMBL345157 Bioactive AGN-PC-075U6C
CFAMM00370214 CHEMBL154990 Bioactive AGN-PC-075U8V
CFAMM00370207 CHEMBL155433 Bioactive 1-benzhydryl-1-[3-(4-hydroxy-3-methoxyphenyl)propyl]-3-(2-phenylethyl)thiourea
CFAMM00370220 CHEMBL356682 Bioactive AGN-PC-075U8A
CFAMM00370213 CHEMBL267205 Bioactive AGN-PC-075U8U

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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