CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6194
Family Name Glycylpeptide N-tetradecanoyltransferase 2 and Glycylpeptide N-tetradecanoyltransferase 1 inhibitor AC1LAMUT family
No. of Seeds 8 No. of Other Members 10
Family Centroid CFAMM00370425 Functional Category Bioactive with Natural Product
Superfamily Glycylpeptide N-tetradecanoyltransferase 2 and Glycylpeptide N-tetradecanoyltransferase 1 inhibitor AC1LAMUT Superfamily
Class Class 2009

Cousin Family NamesSeedsMembers
Multidrug resistance-associated protein 1 Inhibitor Biricodar ... 6 40
5-hydroxytryptamine receptor 1A Ligand Sun N4057 Family 2 86
Aromatase Inhibitor 2-phenyl-3-pyridin-4-ylmethylene-chroman-4... 3 30
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
MO15-related protein kinase Pfmrk Inhibitor WR-289010 Family 2 506
Oxytocin receptor and Vasopressin V1a receptor Ligand L-372662... 31 23
Renin Inhibitor CP-305202 Family 9 30
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 20 28
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
Acetylcholinesterase and Butyrylcholinesterase inhibitor [3-[[... 3 68
Glycylpeptide N-tetradecanoyltransferase 2 and Glycylpeptide N... 2 0
Endothelin-1 receptor ligand SureCN8118632 family 4 5
Cholinesterase and Acetylcholinesterase inhibitor 5-hydroxy-7-... 5 19
Melanin-concentrating hormone receptor 1 ligand 3-[6-[3-(dimet... 1 13
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Serine/threonine-protein kinase pim-1 inhibitor (2Z)-6-methoxy... 1 5
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 1 0
Acetylcholinesterase and Cholinesterase inhibitor 3-[(E)-3-[1-... 3 14
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 2 6
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 3
Aromatase inhibitor isoflavone deriv. 5m family 1 0
Aromatase inhibitor (4-chlorophenyl)-(6-methoxy-1-benzofuran-2... 1 4
Ras-related protein Rab-9A and Niemann-Pick C1 protein inhibit... 1 0


External ID

Functional Category

Molecule Name

CFAMM00370408 CHEMBL170807 Bioactive AC1L9U0H
CFAMM00370414 CHEMBL155301 Bioactive AC1LAMUW
CFAMM00370425 CHEMBL158172 Bioactive AC1LAMUT
CFAMM00370411 CHEMBL355250 Bioactive AC1L9U0E
CFAMM00370417 CHEMBL347048 Bioactive AC1LAMV2
CFAMM00370423 CHEMBL347895 Bioactive AC1LAMUN
CFAMM00370416 CHEMBL345893 Bioactive AC1LAMUZ
CFAMM00370409 CHEMBL155469 Bioactive AC1LAMVE

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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