Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.
CFAM Family ID CFFBM62 Family Name Renin inhibitor benzyl N-[3-[[(2S,4S,5S)-6-cyclohexyl-4-hydroxy-5-[[(2S)-2-[(2S)-1-[4-(methoxymethoxy)piperidin-1-yl]-1-oxo-3-phenylpropan-2-yl]oxyhexanoyl]amino]-2-propan-2-ylhexanoyl]amino]propyl]carbamate family No. of Seeds 2
No. of Other Members 0
Family Centroid CFAMM00306581 Functional Category Bioactive
Superfamily Renin Binder Superfamily Class Class 232
Cousin Family Names Seeds Members Flovagatran family 12 546 Renin Inhibitor CP-80794 Family 16 112 Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348 Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131 Beta-secretase 1 Inhibitor MMI-175 Family 30 137 Integrin beta-3 Inhibitor RWJ-53419 Family 6 65 Plasmepsin-1 Inhibitor SC-5003 Family 93 173 Neuromedin-K receptor Ligand PD-160946 Family 10 32 Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24 Caspase-1 Inhibitor Z-vad-cho Family 8 34 Caspase-4 and Cathepsin D Inhibitor Grassystatin A Family 24 6 Genome polyprotein Inhibitor Acasp-glu-cha-val-prb-cys Family 13 18 Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor 3114... 8 9 Renin inhibitor (2S,4S,5S)-N-butyl-6-cyclohexyl-4-hydroxy-5-[[... 12 1 Renin inhibitor (2S,4S,5S)-N-(4-aminobutyl)-6-cyclohexyl-4-hyd... 32 2 Renin inhibitor (2S,4S,5S)-N-[3-[[amino-(cyanoamino)methyliden... 7 0 Renin inhibitor (2S,4S,5S)-6-cyclohexyl-4-hydroxy-5-[[(2S)-2-[... 1 0 Pol polyprotein inhibitor benzyl N-[(2S,3R)-1-[[(2S,3R,4R)-4-(... 5 26 Pol polyprotein inhibitor benzyl N-[(2S)-1-[[(2S,3S,4R,5S)-3,4... 21 5 Renin and Cathepsin D inhibitor (2S)-N-[(2S,3R,4S)-1-cyclohexy... 13 2 Pol polyprotein inhibitor (2S)-4-benzyl-1-[(2S,4R)-4-benzyl-2-... 10 4 Cathepsin B and Calpain-2 catalytic subunit inhibitor AGN-PC-0... 2 2 Cathepsin B and Calpain-1 catalytic subunit inhibitor AGN-PC-0... 3 1 Pol polyprotein inhibitor benzyl N-[(2S,3R)-4-[(3aR,6S,7aS)-6-... 3 2 Pol polyprotein inhibitor AC1LADQG family 7 1 Pol polyprotein inhibitor methyl (2S)-2-[[(2S,3R)-2-[[1-[(2R,3... 1 0 Pol polyprotein inhibitor benzyl N-[(2S)-4-amino-1-[[(2S,3R)-4... 2 1 Renin inhibitor AGN-PC-076HPD family 1 0 Pol polyprotein inhibitor AC1LA3C0 family 2 18 Renin inhibitor (2S)-2-[(2S)-1-(azetidin-1-yl)-1-oxo-3-phenylp... 1 0 Cathepsin D and Beta-secretase 1 inhibitor benzyl 3-[[(2R,3S)-... 1 0
CFAM Mol ID
External ID
Functional Category
Molecule Name
CFAMM00306582 CHEMBL50217 Bioactive
benzyl N-[(3S,5S,6S)-7-cyclohexyl-5-hydroxy-6-[[(2S)-2-[(2S)-1-[4-(methoxymethoxy)piperidin-1-yl]-1-oxo-3-phenylpropan-2-yl]oxyhexanoyl]amino]-2-methylheptan-3-yl]carbamate CFAMM00306581 CHEMBL100949 Bioactive
benzyl N-[3-[[(2S,4S,5S)-6-cyclohexyl-4-hydroxy-5-[[(2S)-2-[(2S)-1-[4-(methoxymethoxy)piperidin-1-yl]-1-oxo-3-phenylpropan-2-yl]oxyhexanoyl]amino]-2-propan-2-ylhexanoyl]amino]propyl]carbamate
CFAM Mol ID
External ID
Functional Category
Molecule Name
Statistics of CFAM Database
490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
How to cite our database
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering.
Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
Last update by
2014.08.29
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