CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6208
Family Name Integrin beta-1 and Integrin alpha-4 inhibitor (3R)-3-[[(2S)-1-(3,5-dichlorophenyl)sulfonylazetidine-2-carbonyl]amino]-3-(4-methoxyphenyl)propanoic acid family
No. of Seeds 12 No. of Other Members 0
Family Centroid CFAMM00370510 Functional Category Bioactive
Superfamily Integrin beta-1 and Integrin alpha-4 Binder Superfamily 3
Class Class 2455

Cousin Family NamesSeedsMembers
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6368456 f... 3 23
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6367561 f... 20 12
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5686971 f... 19 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[4-(ben... 12 20
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[1-(ben... 6 5
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 9 2
Integrin beta-1 and Integrin alpha-4 inhibitor (4S)-4-[benzene... 7 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5686827 f... 7 3
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5687185 f... 7 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00370518 CHEMBL348323 Bioactive (3R)-3-[[(2S)-1-(3,5-dichlorophenyl)sulfonylazetidine-2-carbonyl]amino]-3-(4-phenoxyphenyl)propanoic acid
CFAMM00370511 CHEMBL156297 Bioactive (3R)-3-[[(2S)-1-(3,5-dichlorophenyl)sulfonylazetidine-2-carbonyl]amino]-3-[4-(difluoromethoxy)phenyl]propanoic acid
CFAMM00370517 CHEMBL357927 Bioactive (3R)-3-[[(2S)-1-(3,5-dichlorophenyl)sulfonylazetidine-2-carbonyl]amino]-3-[4-(2,2,2-trifluoroethoxy)phenyl]propanoic acid
CFAMM00370510 CHEMBL82313 Bioactive (3R)-3-[[(2S)-1-(3,5-dichlorophenyl)sulfonylazetidine-2-carbonyl]amino]-3-(4-methoxyphenyl)propanoic acid
CFAMM00370516 CHEMBL442769 Bioactive (3R)-3-(4-cyclopentyloxyphenyl)-3-[[(2S)-1-(3,5-dichlorophenyl)sulfonylazetidine-2-carbonyl]amino]propanoic acid
CFAMM00370509 CHEMBL349783 Bioactive (3R)-3-[[(2S)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid
CFAMM00370515 CHEMBL348393 Bioactive (3R)-3-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylazetidine-2-carbonyl]amino]-3-(4-methoxyphenyl)propanoic acid
CFAMM00370508 CHEMBL348167 Bioactive (3R)-3-[[(2S)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-(trifluoromethoxy)phenyl]propanoic acid
CFAMM00370514 CHEMBL155372 Bioactive SureCN7228306
CFAMM00370513 CHEMBL155865 Bioactive (3R)-3-(4-cyclopropyloxyphenyl)-3-[[(2S)-1-(3,5-dichlorophenyl)sulfonylazetidine-2-carbonyl]amino]propanoic acid
CFAMM00370519 CHEMBL157978 Bioactive SureCN7227985
CFAMM00370512 CHEMBL347919 Bioactive (3R)-3-[[(2S)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-(4-ethoxyphenyl)propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27257 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543